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Recombinant SARS-CoV-2 (Wuhan-Hu-1) Spike Glycoprotein (Full Length, 1-1211), C-6×His-tagged

Cat.No. : S-654S
Product Overview : Recombinant full-length SARS-CoV-2 spike glycoprotein, manufactured in Chinese hamster ovary (CHO) cells to high yield and purity. The furin cleavage site (amino acids 682-685) has been mutated from RRAR to SRAS and the transmembrane domain and intravirion part replaced with a glycine-serine linker and a His-tag. Horseradish peroxidase conjugated protein also available. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.
  • Specification
  • Gene Information
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Description : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.
Source : CHO
Species : SARS-CoV-2 (Wuhan-Hu-1)
Tag : C-6×His
Form : Liquid
Molecular Mass : Expected Molecular Weight: 134 kDa
Observed Molecular Weight: 170 kDa
Protein Length : 1-1211
Purity : > 95%
Applications : ELISA
Storage : Short Term Storage: -80 centigrade
Long Term Storage: -80 centigrade
Storage Buffer : Dulbecco's phosphate buffered saline (DPBS), pH 7.4.
Shipping : Dry Ice
Gene Name : S surface glycoprotein [ Severe acute respiratory syndrome coronavirus 2 ]
Official Symbol : S
Synonyms : S; surface glycoprotein; structural protein; spike protein
Gene ID : 43740568
Protein Refseq : YP_009724390
UniProt ID : P0DTC2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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