ARF3 Protein, ADP-ribosylation factor 3


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Official Full Name ADP-ribosylation factor 3
Background ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D.The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
Synonyms ARF3; ADP-ribosylation factor 3; small GTP binding protein; ADP ribosylation factor 3; ARF3_HUMAN
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Arf3-635M Recombinant Mouse Arf3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ARF3-237H Recombinant Human ARF3, His tagged E.coli His
    Human ARF3-26994TH Recombinant Human ARF3, His-tagged E.coli His
    Human ARF3-6867H Recombinant Human ADP-Ribosylation Factor 3, His-tagged E.coli His
    Human ARF3-745H Recombinant Human ARF3 protein, GST-tagged Wheat Germ GST
    Human ARF3-8759HCL Recombinant Human ARF3 293 Cell Lysate HEK293 N/A
    Human ARF3-9800H Recombinant Human ARF3, GST-tagged E.coli GST
    Mouse ARF3-1839M Recombinant Mouse ARF3 Protein Mammalian Cell His
    Rat Arf3-3207R Recombinant Rat Arf3, His-tagged E.Coli or Yeast His
    Rat ARF3-749R Recombinant Rat ARF3 Protein Mammalian Cell His

    ARF3 involved in several pathways and played different roles in them. We selected most pathways ARF3 participated on our site, such as Endocytosis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis KIF5A; SMAD2; CBLC; TGFB3; EHD4; TFRC; STAM2; VPS26A; SH3GL3; HSC70
    Metabolism SYT5; CPT2; SLC46A1; SLC25A13; COX10; YAP1; NUDT5; FABP11B; IP6K3; MED18
    Metabolism of lipids and lipoproteins PMVK; ABHD4; ECI1; SLC25A1; THEM5; CPT2; FAAH2; ALOX5B.2; GDF1; OSBP
    Phospholipid metabolism SACM1L; CEPT1A; CPNE6; AWAT1; FIG4; PLBD1; ABHD4; PHOSPHO1; SLC44A5B; SACM1LB
    Synthesis of PIPs at the Golgi membrane TPTE; SACM1LA; FIG4; SACM1L; ARF3; SACM1LB

    ARF3 has several biochemical functions, for example, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARF3 itself. We selected most functions ARF3 had, and list some proteins which have the same functions with ARF3. You can find most of the proteins on our site.

    Function Related Protein
    GTP binding THG1L; RAB2A; RAB35; GCH1; RAB9A; RAP2AB; RHOG; RAB26; RHOA; ANXA6
    GTPase activity TUBB2; DNM2A; RAB5C; EFTUD1; EEF1A2; GNAQ; ARL1; GNAI2A; RAB18; TUFM

    ARF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARF3.

    Kif1c; Bach1; Proser1; Bles03; ARFIP2; ATN1; MAPK13

    Nakazawa, Y; Hiraguri, A; et al. The dsRNA-binding protein DRB4 interacts with the Dicer-like protein DCL4 in vivo and functions in the trans-acting siRNA pathway. PLANT MOLECULAR BIOLOGY 63:777-785(2007).
    Padilla, PI; Pacheco-Rodriguez, G; et al. Nuclear localization and molecular partners of BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101:2752-2757(2004).

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