atg10
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  • Official Full Name
  • autophagy related 10
  • Background
  • Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
  • Synonyms
  • ATG10; autophagy related 10; APG10; APG10L; pp12616; ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog;
Cat.#:ATG10-7174HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATG10 Autophagy Related 10 Homolog (S. cerevisiae), His-tagged
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Cat.#:ATG10-942HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATG10 protein, GST-tagged
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Cat.#:ATG10-9968HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATG10, GST-tagged
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Cat.#:ATG10-2073MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ATG10 Protein
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Cat.#:ATG10-3489ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ATG10
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Cat.#:ATG10-8627HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ATG10 293 Cell Lysate
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Involved Pathway

ATG10 involved in several pathways and played different roles in them. We selected most pathways ATG10 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of autophagy
INSB; IFNA5; ATG16L1; IFNA7; GABARAPL1; Ifna11; ULK2; ATG10; ULK1; IFNPHI3

Protein Function

ATG10 has several biochemical functions, for example, Atg12 transferase activity, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG10 itself. We selected most functions ATG10 had, and list some proteins which have the same functions with ATG10. You can find most of the proteins on our site.
Function
Related Protein
Function Atg12 transferase activity
Related Protein ATG10; ATG3
Function ligase activity
Related Protein UHRF1; MYLIPB; HUWE1; UBE3A; RNF182; ATG10; RNF144A; RNF144AB; HECW1B; NSMCE1

Interacting Protein

ATG10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG10.
GABARAP; GABARAPL2; MAP1LC3C; MAP1LC3B; GABARAPL1; MAP1LC3B2; HAT1; ATG12; ATG7; MAP1B; USP11; RBBP7; USP7; ATG3; ATG4B; q81sn0_bacan

ATG10 Related Articles

Pulliero, A; Seydel, A; et al. Oxidative Damage and Autophagy in the Human Trabecular Meshwork as Related with Ageing. PLOS ONE 9:-(2014).
Zhang, LS; Zhang, J; et al. Autophagy in Pancreatic Acinar Cells in Caerulein-treated Mice: Immunolocalization of Related Proteins and Their Potential as Markers of Pancreatitis. TOXICOLOGIC PATHOLOGY 42:435-457(2014).