ATG10
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Official Full Name
autophagy related 10
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Overview
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008] -
Synonyms
ATG10; autophagy related 10; APG10; APG10L; pp12616; ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- T7
- C
- Involved Pathway
- Protein Function
- Interacting Protein
- ATG10 Related Articles
- ATG10 Related Research Area
ATG10 involved in several pathways and played different roles in them. We selected most pathways ATG10 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of autophagy | IFNA14;IFNA2;IFNA13;GABARAPL1;ATG12;IFNG1-2;IFNA8;Ifna15;ULK2 |
ATG10 has several biochemical functions, for example, Atg12 transferase activity, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG10 itself. We selected most functions ATG10 had, and list some proteins which have the same functions with ATG10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Atg12 transferase activity | ATG3;ATG10 |
| ligase activity | MARCH2;DTX4;DTX1;SIAH2;ITCH;NEURL1B;MSL2;RLIM;TRIM17 |
ATG10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG10.
GABARAP; GABARAPL2; MAP1LC3C; MAP1LC3B; GABARAPL1; MAP1LC3B2; HAT1; ATG12; ATG7; MAP1B; USP11; RBBP7; USP7; ATG3; ATG4B; q81sn0_bacan
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