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ATN1

Official Full Name

atrophin 1
Overview

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Feb 2010]
Synonyms

ATN1; atrophin 1; B37; HRS; NOD; DRPLA; D12S755E; atrophin-1; dentatorubral-pallidoluysian atrophy protein;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
E.Coli or Yeast
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ATN1-3772H	Recombinant Human ATN1, His-tagged	E.Coli or Yeast	His	1190	Inquiry
Human	ATN1-955H	Recombinant Human ATN1 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ATN1-424H	Recombinant Human ATN1 Protein, His-tagged	E.coli	His	Asp879~Leu1190	Inquiry
Mouse	Atn1-3773M	Recombinant Mouse Atn1, His-tagged	E.Coli or Yeast	His	1175	Inquiry
Mouse	ATN1-2096M	Recombinant Mouse ATN1 Protein	Mammalian Cell	His		Inquiry
Mouse	ATN1-836M-B	Recombinant Mouse ATN1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ATN1-836M	Recombinant Mouse ATN1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

ATN1 involved in several pathways and played different roles in them. We selected most pathways ATN1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ATN1 has several biochemical functions, for example, protein binding, protein domain specific binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATN1 itself. We selected most functions ATN1 had, and list some proteins which have the same functions with ATN1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	LAMTOR1;BAI2;PITX2;FCGR2B;RAB41;IFNAR2;NPY1R;CLC;SFTPC
protein domain specific binding	HIST1H4H;TWIST2;IPCEF1;SKI;KCNN2;DDC;ST13;GSN;VPS4A
transcription corepressor activity	TAF9B;LDB1;CBFA2T2;TSG101;JUNB;BASP1;NR0B1;SIRT6;HDAC9

ATN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATN1.

BAIAP2; SIAH1; TRIP6; PLEKHA5; RBFOX1; PLSCR1; PSME3; EWSR1; Dlg4; MEGF11