|Official Full Name||atrophin 1|
|Background||Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Feb 2010]|
|Synonyms||ATN1; atrophin 1; B37; HRS; NOD; DRPLA; D12S755E; atrophin-1; dentatorubral-pallidoluysian atrophy protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ATN1 involved in several pathways and played different roles in them. We selected most pathways ATN1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
ATN1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ATN1 itself. We selected most functions ATN1 had, and list some proteins which have the same functions with ATN1. You can find most of the proteins on our site.
|protein binding||CIB2; Trl; TMEM11; SNX7; DAPK3; C12orf50; ZNF148; TREX1; C8orf33; FUBP1|
|protein domain specific binding||SERPINB1A; RAP2B; NEFL; RARA; ODF1; TFDP2; ACSL3; PLG; YWHAB; PLAUR|
|transcription corepressor activity||ZNF593; MXI1; CSDA; BATF3; KCTD1; MECP2; ZNF274; E2F8; CDYL; RARA|
ATN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATN1.
BAIAP2; SIAH1; TRIP6; PLEKHA5; RBFOX1; PLSCR1; PSME3; EWSR1; Dlg4; MEGF11