atn1
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  • Official Full Name
  • atrophin 1
  • Background
  • Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Feb 2010]
  • Synonyms
  • ATN1; atrophin 1; B37; HRS; NOD; DRPLA; D12S755E; atrophin-1; dentatorubral-pallidoluysian atrophy protein;
Cat.#:ATN1-424HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATN1 Protein, His-tagged
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Cat.#:ATN1-3772HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ATN1, His-tagged
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Cat.#:ATN1-955HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATN1 protein, GST-tagged
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Cat.#:ATN1-2096MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ATN1 Protein
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Cat.#:Atn1-3773MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Atn1, His-tagged
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Protein Function

ATN1 has several biochemical functions, for example, protein binding, protein domain specific binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATN1 itself. We selected most functions ATN1 had, and list some proteins which have the same functions with ATN1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein PTBP3; RAB43; OLIG3; EEF1E1; MOAP1; MRPS6; CEP55; KIFC3; RTF1; a
Function protein domain specific binding
Related Protein ZNF521; RHOA; COX4I2; HIST2H4A; CNTROB; FOXA3; CEP68; STX1A; RXRA; SFN
Function transcription corepressor activity
Related Protein TOB1; PPP1R13L; MXD4; E2F8; E4F1; WWTR1; HDAC7; SKOR2; CTBP2A; GPS2

Interacting Protein

ATN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATN1.
BAIAP2; SIAH1; TRIP6; PLEKHA5; RBFOX1; PLSCR1; PSME3; EWSR1; Dlg4; MEGF11