Recombinant Human ATN1 Protein, His-tagged


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Recombinant Human ATN1 Protein, His-tagged

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Cat.No. : ATN1-424H
Product Overview : Recombinant Human ATN1(Asp879~Leu1190) fused with His tag at N-terminal was expressed in E. coli.
Description : Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 38.2kDa
Protein length : Asp879~Leu1190
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Figure :

Gene Name : ATN1 atrophin 1 [ Homo sapiens ]
Official Symbol : ATN1
Synonyms : ATN1; atrophin 1; D12S755E, dentatorubral pallidoluysian atrophy (atrophin 1) , DRPLA; atrophin-1; B37; dentatorubral-pallidoluysian atrophy protein; HRS; NOD; DRPLA; D12S755E;
Gene ID : 1822
mRNA Refseq : NM_001007026
Protein Refseq : NP_001007027
MIM : 607462
UniProt ID : P54259

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