ATP1B2
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Official Full Name
ATPase, Na+/K+ transporting, beta 2 polypeptide
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Overview
Na+/K+-ATPase (fully Sodium-Potassium Adenosine Triphosphatase, also known as the Na+/K+ pump, sodium-potassium pump, or sodium pump, for short) is an enzyme (EC 3.6.3.9) located in the plasma membrane (to be specific, an electrogenic transmembrane ATPase) in all animals. -
Synonyms
AMOG; AT1B2; ATP1B2; ATPase Na+/K+ transporting beta 2 polypeptide; ATPB2; ATPB2S; MGC93648; Na+/K+ -ATPase beta 2 subunit; RATATPB2S; Sodium/potassium-dependent ATPase subunit beta-2; Sodium/potassium-transporting ATPase subunit beta-2; ATPase, Na+/K+ transporting, beta 2 polypeptide; adhesion molecule on glia; sodium/potassium-dependent ATPase beta-2 subunit; sodium/potassium-transporting ATPase beta-2 chain;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
ATP1B2 involved in several pathways and played different roles in them. We selected most pathways ATP1B2 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cGMP-PKG signaling pathway | IRS1;RGS2;GNAI1;PPP1CB;SLC8A2;PPP1CC;SLC25A31;MYLK;Adcy4 |
| cAMP signaling pathway | RAC1;ATP2B4;CNGA4;MAP2K1;AMH;GRIN2C;HTR1F;GRIN3A;PIK3CB |
| Cardiac muscle contraction | SLC9A1;COX4I1;CACNA2D1;UQCR11;MYH15;CACNG7;COX7C;ATP1B2A;ATP1A2 |
| Adrenergic signaling in cardiomyocytes | MAPK12;ADRB2;GNAI3;ATP1A2;MYL2B;CACNA1C;MAPK11;CACNG8;PIK3CD |
| Insulin secretion | GCG;CREB3L3;SNAP25;FFAR1;FXYD2;RYR2;PLCB3;PRKACG;PRKACA |
| Thyroid hormone synthesis | CREB5;ATP1B4;TSHB;PLCB1;PLCB2;ATP1A1;PRKACA;ATF4;PRKACB |
| Thyroid hormone signaling pathway | PLCB2;GSK3B;AKT2;AKT1;DIO1;PLCZ1;PIK3CB;PLCB1;BAD |
| Aldosterone-regulated sodium reabsorption | PDPK1;ATP1A4;PIK3CB;ATP1A2;INS1;KCNJ1;SCNN1G;IRS1;HSD11B2 |
| Endocrine and other factor-regulated calcium reabsorption | ATP1B2;PLCB3;KLK1B3;BDKRB2;ESR1;KLK1B26;KLK1B11;PRKACA;PRKACB |
| Proximal tubule bicarbonate reclamation | CA4;FXYD2;GLS;MDH1;ATP1B4;Car4;CA2;Car2;SLC4A4 |
| Salivary secretion | ATP1A2;RYR3;AMY1A;HTN1;CD38;CALML5;NOS1;CST1;ATP1B4 |
| Gastric acid secretion | ACTB;GAST;GNAS;SSTR2;ATP1B2;PLCB4;CALML5;KCNJ2;HRH2 |
| Pancreatic secretion | ATP2A2;RAP1B;RYR2;CPA3;CLCA3;CA2;PLA2G1B;TPCN2;CCKAR |
| Carbohydrate digestion and absorption | ATP1A3;SLC2A5;HK1;SLC2A2;SLC5A1;AMY2A3;G6PC;PIK3CG;ATP1B4 |
| Protein digestion and absorption | COL18A1;DPP4;KCNQ1;PRSS3;CPB2;KCNJ13;FXYD2;COL6A4;CELA3A |
| Bile secretion | ADCY7;ATP1A4;AQP1;SLC9A3;SLC4A4;ABCB11;NR1H4;CA2;HMGCR |
| Mineral absorption | CYBRD1;MT1X;ATP1A4;MT1A;VDR;SLC26A6;ATP1A1;ATP1B4;SLC46A1 |
ATP1B2 has several biochemical functions, for example, ATPase activator activity, ATPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B2 itself. We selected most functions ATP1B2 had, and list some proteins which have the same functions with ATP1B2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase activator activity | ATP1B3;ATP1B2;TOR1AIP2;DNAJB6;ATP1B1;DNAJB1;DNAJC15;DNAJC10;MYBPC3 |
| ATPase binding | ATP6V1G1;DRD1;ATP6V1E1;PLN;ATP6V0A4;ATXN3;SDF2L1;PEX19;DNAJC10 |
| protein binding | SIX3;RPIA;INO80E;NPLOC4;CAMK2D;GDPD5;TDRD9;FBN2;IFNA2 |
| sodium:potassium-exchanging ATPase activity | ATP1A1B;ATP1A3;ATP4A;ATP1A1A.4;ATP1B3;ATP12A;ATP1A1;ATP1A1A.1;ATP1A4 |
| contributes_to sodium:potassium-exchanging ATPase activity | ATP1A1;ATP1B2;ATP1B3;ATP1B1;ATP1A2 |
ATP1B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B2.
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