bmp1
Share
  • Official Full Name
  • bone morphogenetic protein 1
  • Background
  • This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
  • Synonyms
  • BMP1; bone morphogenetic protein 1; PCP; TLD; OI13; PCP2; PCOLC; mammalian tolloid protein; procollagen C-proteinase 3; procollagen C-endopeptidase;
Cat.#:BMP1-571HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Bone Morphogenetic Protein 1, His-tagged
+Inquiry
Cat.#:BMP1-10247HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMP1, His-tagged
+Inquiry
Cat.#:BMP1-256HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP1 Protein, GST-tagged
+Inquiry
Cat.#:BMP1-26314THTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BMP1 protein, GST-tagged
+Inquiry
Cat.#:BMP1-662HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMP1 protein, His & GST-tagged
+Inquiry
Cat.#:BMP1-707HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human BMP1, His-tagged
+Inquiry
Cat.#:BMP1-2428MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BMP1 Protein
+Inquiry
Cat.#:Bmp1-663MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bmp1 protein, His-tagged
+Inquiry
Cat.#:BMP1-546RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey BMP1 Protein, His-tagged
+Inquiry
Cat.#:BMP1-8436HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human BMP1 293 Cell Lysate
+Inquiry

Involved Pathway

BMP1 involved in several pathways and played different roles in them. We selected most pathways BMP1 participated on our site, such as Adipogenesis, Anchoring fibril formation, Assembly of collagen fibrils and other multimeric structures, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
CELF1; MEF2B; KLF6; EGR2B; FOXC2; KLF7; HMGA1-RS1; EGR2; GATA2A; NDN
Anchoring fibril formation
BMP1B; TLL2; TLL1; BMP1A; BMP1
Assembly of collagen fibrils and other multimeric structures
COL4A6; COL5A3B; COL2A1; CD151; ABHD1; CTSS; LOXL3; COL8A1; MMP20; COL6A1
Cardiac Progenitor Differentiation
NOG; BMP1; NIPAL1; TBX20; SOX1; IRX4; TBX5; LIN28A; SIRPA; ZFP42
Collagen biosynthesis and modifying enzymes
COL9A1A; COL17A1; COL23A1; TLL1; COL1A1; COL10A1A; PCOLCEB; COL15A1B; COL4A4; COL5A3A
Collagen formation
COL28A1D; COL1A1; COL4A3; BMP1; COL8A1; PRP; TLL2; COL13A1; CTSS; LOXL1
Crosslinking of collagen fibrils
BMP1; TLL2; LOXL1; ABHD1; LOXL3; PCOLCE; BMP1B; LOXL4; LOX; BMP1A
Degradation of the extracellular matrix
ADAM8A; MMP17; COL17A1; CMA1; ADAM15; COL9A1; KLK7; CTSB; ADAM9; CAPNS1

Protein Function

BMP1 has several biochemical functions, for example, calcium ion binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP1 itself. We selected most functions BMP1 had, and list some proteins which have the same functions with BMP1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PCDH1G2; PLCD1B; ADAMTS13; RCVRNA; CANT1A; PCDH2G29; ANXA3; SWAP70B; S100A7A; PPP3CB
Function cytokine activity
Related Protein TGFB1; SPAW; CMTM8; IFNPHI2; BMP7B; BMP2; BMP7A; SPP1; IFNA16; TNFSF15
Function growth factor activity
Related Protein EFEMP1; JAG1; BMP8B; Il2; HBEGFB; VHL; IL11; AGT; MANF; IL4
Function metalloendopeptidase activity
Related Protein HE2; HE1A; MMP19; ADAM20; MMP30; MIPEP; ADAM5; ADAM32; ADAMTSL4; ADAMTSL5
Function metallopeptidase activity
Related Protein PGCP; ADAM5; ERAP2; ERMP1; MMP1A; ADAM2; MEP1A.1; PSMD14; MMP13A; ENPEP
Function peptidase activity
Related Protein MMP23BB; CTSBB; ELA2L; PM20D1.1; ELA3L; PGCP; KLK1B1; ST14A; STAMBPA; USP2A
Function protein binding
Related Protein LUC7L2; AKT1; NUDT10; NDUFB9; CYBRD1; CCER1; MS4A1; NAV1; SOAT1; RAF1
Function zinc ion binding
Related Protein RYBP; POLR2K; MYLIP; RAG2; EWSR1A; RNF138; RBX1; MT1; MMP26; FTR72

Interacting Protein

BMP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP1.
MSTN; CHRD; TP53; ADRA1A; YLPM1; GEM; Uso1

BMP1 Related Articles

Purushotham, S; Deivanayagam, C; et al. Cloning, expression and purification of the SRCR domains of glycoprotein 340. PROTEIN EXPRESSION AND PURIFICATION 90:67-73(2013).
Grgurevic, L; Macek, B; et al. Bone morphogenetic protein (BMP)1-3 enhances bone repair. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 408:26-+(2011).

BMP1 Related Gene Family

TGF