BMP1 Protein, bone morphogenetic protein 1


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Official Full Name bone morphogenetic protein 1
Background This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
Synonyms BMP1; bone morphogenetic protein 1; PCP; TLD; OI13; PCP2; PCOLC; mammalian tolloid protein; procollagen C-proteinase 3; procollagen C-endopeptidase;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMP1-10247H Recombinant Human BMP1, His-tagged E.coli His
    Human BMP1-256H Recombinant Human BMP1 Protein, GST-tagged Wheat Germ GST
    Human BMP1-26314TH Recombinant Human BMP1 protein, GST-tagged Wheat Germ GST
    Human BMP1-571H Recombinant Human Bone Morphogenetic Protein 1, His-tagged NS0 His
    Human BMP1-662H Recombinant Human BMP1 protein, His & GST-tagged E.coli His/GST
    Human BMP1-707H Recombinant Human BMP1, His-tagged NS0 His
    Human BMP1-8436HCL Recombinant Human BMP1 293 Cell Lysate HEK293 N/A
    Mouse BMP1-2428M Recombinant Mouse BMP1 Protein Mammalian Cell His
    Mouse Bmp1-663M Recombinant Mouse Bmp1 protein, His-tagged E.coli His
    Rhesus Macaque BMP1-546R Recombinant Rhesus monkey BMP1 Protein, His-tagged Mammalian Cell His

    BMP1 involved in several pathways and played different roles in them. We selected most pathways BMP1 participated on our site, such as Adipogenesis, Anchoring fibril formation, Assembly of collagen fibrils and other multimeric structures, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis CEBPD; CISD1; CREB1; KLF7A; KLF5; HMGA1; BMP1; EGR2; FRZB; CELF1
    Anchoring fibril formation TLL1; BMP1A; BMP1B; TLL2; BMP1
    Assembly of collagen fibrils and other multimeric structures PCOLCE; BMP1; ABHD1; MMP20; COL6A2; COL4A6; BMP1A; CTSB; PLEC; MMP13
    Cardiac Progenitor Differentiation LIN28A; TBX5; TBX20; LIN28B; ZFP42; NOG; SOX1; NIPAL1; BMP1; T
    Collagen biosynthesis and modifying enzymes COL11A1B; LEPREL1; COL28A1; COL5A3B; COL9A3; EMID2; COL5A3A; BMP1A; COL17A1A; COL15A1B
    Collagen formation COL5A3A; ADAMTS2; TLL1; COL4A5; CRTAP; LOXL2; COL28A1D; COL4A3; COL6A2; LOXL4
    Crosslinking of collagen fibrils TLL2; BMP1B; BMP1; LOXL3; BMP1A; LOX; LOXL1; LOXL2; ABHD1; TLL1
    Degradation of the extracellular matrix ADAM8A; COL9A3; ADAMTS4; CTSS; CTRB1; MMP11; TIMP2; TIMP2A; EMID2; MGC174152

    BMP1 has several biochemical functions, for example, calcium ion binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP1 itself. We selected most functions BMP1 had, and list some proteins which have the same functions with BMP1. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ANXA11A; aLA; PROC; CABP7; ZZEF1; MAN1A1; PCDH18A; CCDC48; MYL9A; CASQ1
    cytokine activity GREM2; IL9; BMP15; LIF; LTA; CSF1A; MSTNA; Kitl; OSTN; MIF
    growth factor activity NDP; BMP6; FGF1; IL10; FGF14; NTF3; PDGFD; LACRT; AREG; GPI
    metalloendopeptidase activity ADAMTS16; MEP1A.1; ADAM22; ADAM17; ADAM10A; ADAMTS8; ADAMTS13; C6AST4; ADAMTS18; PITRM1
    metallopeptidase activity ADAM18; MMP30; BMP1; YME1L1; ADAM9; ERAP2; ADAM20; MYSM1; HE1A; ADAMTS7
    peptidase activity CTSB; ADAMTS12; FAM49BA; CAPN3; TMPRSS4A; PSMB9B; AGBL4; BAP1; Ren1; GZMF
    protein binding ARF6; KL; RWDD3; MRPL1; PRH2; RAC3; ATXN3; ALOX5; CCDC28A; AGFG1
    zinc ion binding MYLIP; RORAA; RBM4.1; NR5A5; DPYS; ADAMTS20; BMP1A; TRIM12A; NR4A2B; TRIM46B

    BMP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP1.

    MSTN; CHRD; TP53; ADRA1A; YLPM1; GEM; Uso1

    Purushotham, S; Deivanayagam, C; et al. Cloning, expression and purification of the SRCR domains of glycoprotein 340. PROTEIN EXPRESSION AND PURIFICATION 90:67-73(2013).
    Grgurevic, L; Macek, B; et al. Bone morphogenetic protein (BMP)1-3 enhances bone repair. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 408:26-+(2011).


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