Recombinant Mouse Bmp1 protein, His-tagged

• Cat.No.: Bmp1-663M
• Product Overview: Recombinant Mouse Bmp1 aa. (Gly856~Lys982 (Accession # P98063)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a metalloproteinase that plays an essential role in the formation of the extracellular matrix and is also able to induce ectopic bone formation. Unlike other bone morphogenetic proteins, the protein encoded by this gene is not closely related to transforming growth factor-beta. This protein plays in role several developmental processes. In humans, mutations in this gene are associated with osteogenesis imperfecta and with increased bone mineral density and multiple recurrent fractures. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 22kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Gly856~Lys982
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.9.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Bmp1 bone morphogenetic protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Bmp1
• Synonyms: Bmp1; bone morphogenetic protein 1; Pcp; Tld; bone morphogenetic protein 1; mammalian tolloid protein; procollagen C-proteinase
• Gene ID: 12153
• mRNA Refseq: NM_009755.3
• Protein Refseq: NP_033885.2
• UniProt ID: P98063