bmp10
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  • Official Full Name
  • BMP10 bone morphogenetic protein 10
  • Background
  • FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs, FGF10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells.Recombinant FGF10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre-adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired.
  • Synonyms
  • BMP10; bone morphogenetic protein 10; MGC126783
Cat.#:BMP10-264HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMP10 Protein, His/GST-tagged
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Cat.#:Bmp10-265MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bmp10 Protein, His/GST-tagged
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Cat.#:BMP10-26HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Bone Morphogenetic Protein 10
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Cat.#:Bmp10-575MTag:N/A
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Bone Morphogenetic Protein 10
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Cat.#:BMP10-1081HTag:
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human BMP10
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Cat.#:BMP10-1082HTag:
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human BMP10
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Cat.#:BMP10-257HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP10 Protein, GST-tagged
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Cat.#:BMP10-258HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP10 Protein, GST-tagged
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Cat.#:BMP10-486HTag:
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human BMP10 Protein
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Cat.#:BMP10-2429MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BMP10 Protein
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Cat.#:BMP10-995RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BMP10 Protein
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Cat.#:BMP10-5327CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BMP10
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Cat.#:BMP10-7083ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BMP10
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Cat.#:BMP10-8435HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BMP10 293 Cell Lysate
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Involved Pathway

BMP10 involved in several pathways and played different roles in them. We selected most pathways BMP10 participated on our site, such as Elastic fibre formation, Extracellular matrix organization, Heart Development, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Elastic fibre formation
EFEMP2; MFAP1B; ITGB3A; MFAP1; EFEMP1; BMP10; LOXL1; LTBP2; ABHD1; LOXL2
Extracellular matrix organization
MUSK; COL4A6; DDR2; MMP8; MFAP1; COL28A1A; COL11A1B; MMP10; MFAP3; MMP17
Heart Development
TBX5; HEY2; BMP10; TBX20; FOXC2; FOXH1; NKX2-5; NKX2; SMYD1; FOXC1
Molecules associated with elastic fibres
FBLN1; LTBP2; LTBP4; FBLN2; EFEMP2; MFAP2; MFAP1; BMP10; MFAP1B; MFAP5

Protein Function

BMP10 has several biochemical functions, for example, cytokine activity, growth factor activity, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP10 itself. We selected most functions BMP10 had, and list some proteins which have the same functions with BMP10. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IFNK; IL36G; IFNA16; CER1; IL29; INHBB; CCL6; GM13287; GDF5; IL10
Function growth factor activity
Related Protein CLCF1; NODAL; GSDF; GMFB; LFT2; IGF2B; AMELX; BMP10; FGF6; MDKA
Function hormone activity
Related Protein INSL5; ADCYAP1A; GH1; FSD1; PRL6A1; UCN3; PRL8A8; CSH2; THPO; GAST
Function protein binding
Related Protein SERPINA5; NPBWR2; OSBPL3; WEE1; C14orf169; EFTUD2; PRICKLE1A; ATF7IP; APPBP2; TICAM2
Function receptor serine/threonine kinase binding
Related Protein BMP10
Function telethonin binding
Related Protein CSRP3; BMP10; TTN; MYOZ2; KCNE1
Function transforming growth factor beta receptor binding
Related Protein GDF15; GDF9; NODAL; LRG1; USP15; MSTNB; BMP3; SMAD3; BMP4; AMH

Interacting Protein

BMP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP10.
SERINC3

BMP10 Related Gene Family

TGF