CARD11

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CARD11

Official Full Name caspase recruitment domain family, member 11
Background CARD11/Carma1/Bimp3 belongs to the MAGUK (membrane-associated guanylate kinase) family that typically function as molecular scaffolds in the assembly of multiprotein complexes. MAGUK family members contain an SH3 domain, a PDZ domain and a GuK domain homo
Synonyms CARD11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; bcl10 interacting maguk protein 3; BIMP3; card maguk protein 1; CARMA1; carma 1; card-maguk protein 1; CARD-containing MAGUK protein 1; bcl10-interacti
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Card11-385M Recombinant Mouse Card11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CARD11-6717H Recombinant Human CARD11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CARD11-0391H Recombinant Human CARD11 Protein, GST-Tagged Wheat Germ GST
    Human CARD11-10718H Recombinant Human CARD11, His-tagged E.coli His
    Human CARD11-7850HCL Recombinant Human CARD11 293 Cell Lysate HEK293 N/A
    Mouse CARD11-2728M Recombinant Mouse CARD11 Protein Mammalian Cell His
    Chicken CARD11-1312C Recombinant Chicken CARD11 Mammalian Cell His

    CARD11 involved in several pathways and played different roles in them. We selected most pathways CARD11 participated on our site, such as NF-kappa B signaling pathway, T cell receptor signaling pathway, B cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CARD11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    NF-kappa B signaling pathway IL-8; CCL4L1; NFKBIA; BLNK; IKBKG; RELB; Ccl21c; ERC1; BIRC2; CCL21
    T cell receptor signaling pathway SHB; MUC1; NFATC3; RELA; FYN; RAF1; CARD11; PPP3CC; CBL; VAV3
    B cell receptor signaling pathway PIK3CB; PPP3R1; PIK3AP1; PDPK1A; NFATC1; PTPN6; ARPC2; MALT1; CRKL; RAP2A

    CARD11 has several biochemical functions, for example, CARD domain binding, guanylate kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CARD11 itself. We selected most functions CARD11 had, and list some proteins which have the same functions with CARD11. You can find most of the proteins on our site.

    Function Related Protein
    CARD domain binding MAVS; CARD14; CARD11; RIPK2; C9orf89; CARD9; NOD1
    guanylate kinase activity GUK1; DLG1; TJP2; GUK1B; CASK; DLG4B; MPP2; DLG1L; DLG3; GUK1A
    protein binding BCL2L13; IL17RA; DNMT3L; FIG4; ROBO1; FANCB; MIF; PGR; GTPBP10; CCDC55

    CARD11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CARD11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CARD11.

    BCL10; COPS5; AKT1; MALT1; IKBKG; PDPK1; BCRF1; TAB1; GPS1

    Wang, H; Zhao, J; et al. CARD11 blockade suppresses murine collagen-induced arthritis via inhibiting CARD11/Bcl10 assembly and T helper type 17 response. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 176:238-245(2014).
    Chinen, J; Notarangelo, LD; et al. Advances in basic and clinical immunology in 2013. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 133:967-976(2014).

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