ccnb1
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  • Official Full Name
  • cyclin B1
  • Background
  • The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
  • Synonyms
  • CCNB1; cyclin B1; CCNB; G2/mitotic-specific cyclin-B1; OTTHUMP00000123478; OTTHUMP00000221981; OTTHUMP00000223023; G2/mitotic-specific cyclin B1
Cat.#:CCNB1-0650HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCNB1 Protein, GST-Tagged
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Cat.#:CCNB1-27519THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCNB1, His-tagged
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Cat.#:CCNB1-31593THTag:
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Human CDK1
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Cat.#:CCNB1-353HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCNB1 protein, His/MBP-tagged
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Cat.#:CCNB1-6853HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cyclin B1, His-tagged
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Cat.#:CCNB1-2983MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CCNB1 Protein
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Cat.#:CCNB1-1218RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CCNB1 Protein
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Cat.#:CCNB1-697RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCNB1 Protein, His-tagged
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Cat.#:CCNB1-9062ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CCNB1
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Cat.#:CCNB1-303HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CCNB1 cell lysate
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Involved Pathway

CCNB1 involved in several pathways and played different roles in them. We selected most pathways CCNB1 participated on our site, such as FoxO signaling pathway, Cell cycle, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNB1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
FoxO signaling pathway
BNIP4; IRS1; SGK2; PRKAA1; KLF2A; HRASB; GABARAPA; AGAP2; IGF1R; MAPK14B
Cell cycle
CDK7; MAPRE1; NUPL2; TEX12; NCAPH2; YWHAE2; CCND3; SKP2; ANAPC2; TMPO
Oocyte meiosis
PPP2CA; YWHAB; PGR; ITPR3; CALM4; BTRC; CAMK2B1; CALM; MOS; CCNE2
p signaling pathway
ATM; CD82A; CCND3; PTENB; SERPINB5; RPRMA; TRP53; RRM2B; TNFRSF10B; GADD45AB
Progesterone-mediated oocyte maturation
CDC25A; MAPK12; ANAPC11; MAPK14B; PDE3B; PIK3R3B; INS2; MAPK9; ADCY1B; MOS

Protein Function

CCNB1 has several biochemical functions, for example, histone kinase activity, patched binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNB1 itself. We selected most functions CCNB1 had, and list some proteins which have the same functions with CCNB1. You can find most of the proteins on our site.
Function
Related Protein
Function histone kinase activity
Related Protein CDK1; BAZ1B; CCNB1
Function patched binding
Related Protein DHH; SETD6; PTCH1; BBS1; IHH; CAV1; Shh; CCNB1; SMO
Function protein binding
Related Protein CBL; CDC7; ZNF193; USP14; CHD8; E2F6; TAL2; ZSCAN21; GATA2; FAM46B
Function protein kinase binding
Related Protein PRDX3; RHEB; CAMK2N2; GATA6; PTK2; MAP3K13; GOLGA2; PLCG1; CDK5R1; NEFH

Interacting Protein

CCNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNB1.
CDK1; CDK2; PKMYT1