|Official Full Name||CD177 Molecule|
|Background||CD177 antigen is a protein that in humans is encoded by the CD177 gene. NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971. [supplied by OMIM].|
|Synonyms||CD177 antigen; PRV-1; HNA-2a; NB1 GP; CD177; NB1 glycoprotein; cell surface receptor; polycythemia rubra vera 1; Human neutrophil alloantigen 2a; NB1; PRV1; HNA2A; Polycythemia rubra vera protein 1; CD177 molecule; UNQ595/PRO1181|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CD177 involved in several pathways and played different roles in them. We selected most pathways CD177 participated on our site, such as Cell surface interactions at the vascular wall, Common Pathway of Fibrin Clot Formation, Formation of Fibrin Clot (Clotting Cascade), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD177 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell surface interactions at the vascular wall||GRB7; ITGB1B.1; CXADR; SLC7A6; SLC7A10; CD84; SLC16A8; PROCR; JAM2B; CEACAM1|
|Common Pathway of Fibrin Clot Formation||CD177; CFHL2; PROCR; PRTN3; F13A1B; CFHL1; SERPINA1L; CFHL3; F13A1A.1; CFHL4|
|Formation of Fibrin Clot (Clotting Cascade)||F13A1A.1; PROCR; CFHL4; F3A; PRTN3; SERPINA1L; F3B; CD177; LOC100514666; SERPINE2|
|Hemostasis||RHOB; F3A; IGF2B; SERPINE2; TRPC3; HBB-BH1; SERPINB8; PIK3R6; CEACAM8; KIF15|
CD177 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD177 itself. We selected most functions CD177 had, and list some proteins which have the same functions with CD177. You can find most of the proteins on our site.
|protein binding||INTS10; CBX5; RPS25; MAPKBP1; SECISBP2; HOMER3; PIAS4; FAM125A; PHYHIPL; TBCEL|
CD177 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD177 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD177.