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Recombinant Human CD177 Protein, GST-Tagged

Cat.No. : CD177-0730H
Product Overview : Human CD177 full-length ORF (AAH29167.1, 1 a.a. - 437 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.8 kDa
AA Sequence : MSPVLLLALLGFILPLPGVQALLCQ FGTVQHVWKVSDLPRQWTPKNTSCD SGLGCQDTLMLIESGPQVSLVLSKG CTEAKDQEPRVTEHRMGPGLSLISY TFVCRQEDFCNNLVNSLPLWAPQPP ADPGSLRCPVCLSMEGCLEGTTEEI CPKGTTHCYDGLLRLRGGGIFSNLR VQGCMPQPGCNLLNGTQEIGPVGMT ENCNRKDFLTCHRGTTIMTHGNLAQ EPTDWTTSNTEMCEVGQVCQETLLL LDVGLTSTLVGTKGCSTVGAQNSQK TTIHSAPPGVLVASYTHFCSSDLCN SASSSSVLLNSLPPQAAPVPGDRQC PTCVQPLGTCSSGSPRMTCPRGTTH CYDGYIHLSGGGLSTKMSIQGCVAQ PSSFLLNHTRQIGIFSAREKRDVQP PASQHEGGGAEGLESLTWGVGLALA PALWWGVVCPSC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CD177 CD177 molecule [ Homo sapiens ]
Official Symbol : CD177
Synonyms : CD177; CD177 molecule; CD177 antigen; HNA2A; NB1; polycythemia rubra vera 1; PRV1; NB1 glycoprotein; cell surface receptor; human neutrophil alloantigen 2a; polycythemia rubra vera protein 1; PRV-1; HNA-2a; NB1 GP;
Gene ID : 57126
mRNA Refseq : NM_020406
Protein Refseq : NP_065139
MIM : 162860
UniProt ID : Q8N6Q3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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