cd1b
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  • Official Full Name
  • CD1b molecule
  • Background
  • This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
  • Synonyms
  • CD1B; CD1b molecule; CD1, CD1b antigen , CD1B antigen, b polypeptide; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; R1; CD1; CD1A; MGC125990; MGC125991
Cat.#:CD1B-317RTag:His
Source (Host):HEK293Species:Rhesus
Product nameRecombinant Rhesus CD1B Protein, His-tagged
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Cat.#:CD1B-0734HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD1B Protein, GST-Tagged
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Cat.#:CD1B-3039HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B Protein, MYC/DDK-tagged
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Cat.#:CD1B & B2M-249HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B & B2M protein, His-tagged
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Cat.#:CD1B-10918HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD1B, His-tagged
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Cat.#:CD1B-27106THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD1B
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Cat.#:CD1B-27865THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD1B
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Cat.#:CD1B-344HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD1b molecule, His-tagged
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Cat.#:CD1B-7331HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B, Fc tagged
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Cat.#:CD1B-721RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD1B Protein, His-tagged
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Cat.#:CD1B-2186CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD1B
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Cat.#:CD1B & B2M-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B & B2M cell lysate
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Cat.#:CD1B-1504HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1B cell lysate
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Involved Pathway

CD1B involved in several pathways and played different roles in them. We selected most pathways CD1B participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hematopoietic cell lineage
GYPA; CD1d1; CD19; IL9R; GM13305; CD1A; Kitl; CD38; Fcer2a; CD8B

Protein Function

CD1B has several biochemical functions, for example, beta-2-microglobulin binding, endogenous lipid antigen binding, exogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1B itself. We selected most functions CD1B had, and list some proteins which have the same functions with CD1B. You can find most of the proteins on our site.
Function
Related Protein
Function beta-2-microglobulin binding
Related Protein CD1D; HLA-A; CD1E; FCGRT; CD1B; CD1C; HLA-E; HFE; H2-Q10; CD1D2
Function endogenous lipid antigen binding
Related Protein CD1A; CD1D2; CD1B; CD1C; CD1D; CD1E; CD1d1
Function exogenous lipid antigen binding
Related Protein CD1d1; CD1D; CD1C; CD1E; CD1B; CD1A; CD1D2
Function lipopeptide binding
Related Protein CD1d1; CD1E; CD1C; CD1A; CD1B; CD1D2; TLR6; CD1D
Function protein binding
Related Protein FHL2; ARF6; TRIM28; GADD45B; CD74; CCDC6; MCPH1; KRTAP10-5; RPP25L; PITPNC1

Interacting Protein

CD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CD1B.
B2M

CD1B Related Articles

Romero-Palomo, F; Risalde, MA; et al. Immunohistochemical Detection of Dendritic Cell Markers in Cattle. VETERINARY PATHOLOGY 50:1099-1108(2013).
Kalantari-Dehaghi, M; Anhalt, GJ; et al. Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique. PLOS ONE 8:-(2013).