CDH17

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CDH17

Official Full Name cadherin 17, LI cadherin (liver-intestine)
Background This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.;The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a;transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal;tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral;absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological;organization of liver and intestine. Alternative splicing results in multiple transcript variants.
Synonyms CDH17; cadherin 17, LI cadherin (liver-intestine); cadherin-17; cadherin; HPT 1; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestina
    • Species :
    • Chicken
    • Cynomolgus
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Mouse
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • HlgG1 Fc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Cynomolgus CDH17-1100C Recombinant Cynomolgus CDH17 Protein (Met1-Met787), HlgG1 Fc-tagged HEK293 HlgG1 Fc
    Human CDH17-2043H Recombinant Human CDH17 Protein, His-tagged HEK293 His
    Human CAB11507MH Mouse Anti-Human Cadherin 17, LI Cadherin Monoclonal Antibody Mouse N/A
    Human CDH17-0978H Recombinant Human CDH17 Protein, GST-Tagged Wheat Germ GST
    Human CDH17-2032HCL Recombinant Human CDH17 cell lysate Human Cell N/A
    Human CDH17-2094H Recombinant Human CDH17 protein, His & T7-tagged E.coli His/T7
    Human CDH17-29102TH Recombinant Human CDH17 Wheat Germ N/A
    Human CDH17-3898H Recombinant Human CDH17, His tagged Human Cell His
    Rat CDH17-1289R Recombinant Rat CDH17 Protein Mammalian Cell His
    Rat CDH17-1483RCL Recombinant Rat CDH17 cell lysate Human Cell N/A
    Chicken CDH17-4342C Recombinant Chicken CDH17 Mammalian Cell His
    Zebrafish CDH17-9772Z Recombinant Zebrafish CDH17 Mammalian Cell His

    CDH17 involved in several pathways and played different roles in them. We selected most pathways CDH17 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CTNND1; JUPA; CDH24; CDH13; CDH3; CADM2; ANG; CDH9; CDH11; JUP
    Cell junction organization CDH4; CDH9; CDH18A; CDH12A; CLDN3; PVRL1A; CLDN7; JUPA; RSU1; PLEC
    Cell-Cell communication CLDN3; CDH13; CDH7; CDH10; CDH3; DCC; DSCAMA; SIRPA; FERMT2; INADL
    Cell-cell junction organization CDH5; CDH9; CDH18A; PVRL1A; CDH18; CLDN20; CLDN23; CDH11; F11R.2; CLDN16

    CDH17 has several biochemical functions, for example, calcium ion binding, proton-dependent oligopeptide secondary active transmembrane transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH17 itself. We selected most functions CDH17 had, and list some proteins which have the same functions with CDH17. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PLCB3; PCDH1A6; PCDHB5; FKBP10B; ADAMTS13; EFCAB12; LETM1; MYL10; PCDH15B; CRTAC1
    proton-dependent oligopeptide secondary active transmembrane transporter activity SLC15A1; CDH17
    transporter activity CRABP1; XK; SLC15A5; SLC2A8; SLC2A3A; SLC2A11B; SLC12A10.1; STEAP1; RBP2A; CHP1

    CDH17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH17.

    Funakoshi, S; Shimizu, T; et al. BILL-Cadherin/Cadherin-17 Contributes to the Survival of Memory B Cells. PLOS ONE 10:-(2015).
    Lin, ZH; Zhang, C; et al. Targeting Cadherin-17 Inactivates Ras/Raf/MEK/ERK Signaling and Inhibits Cell Proliferation in Gastric Cancer. PLOS ONE 9:-(2014).

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