cdk2ap1
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  • Official Full Name
  • cyclin-dependent kinase 2 associated protein 1
  • Background
  • The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
  • Synonyms
  • CDK2AP1; cyclin-dependent kinase 2 associated protein 1; CDK2 associated protein 1; cyclin-dependent kinase 2-associated protein 1; doc 1; DOC1; DORC1; p12DOC 1; ST19; CDK2 A1; CDK2-associated protein 1; CDKA1; CDKA1_HUMAN; Cyclin dependent kinase 2 associated protein 1; Deleted in oral cancer 1; DOC 1 related protein; DOC 1R; DOC-1; DOC1R; Putative oral cancer suppressor; OTTHUMP00000239636; OTTHUMP00000239637; OTTHUMP00000239638; OTTHUMP00000239639; OTTHUMP00000239640; Deleted in oral cancer-1; p12DOC-1
Cat.#:CDK2AP1-1005HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDK2AP1 Protein, GST-Tagged
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Cat.#:CDK2AP1-11047HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDK2AP1, GST-tagged
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Cat.#:CDK2AP1-27910THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDK2AP1, His-tagged
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Cat.#:CDK2AP1-27911THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDK2AP1, His-tagged
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Cat.#:CDK2AP1-3201MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CDK2AP1 Protein
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Cat.#:CDK2AP1-3329CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDK2AP1
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Cat.#:CDK2AP1-1936HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDK2AP1, His-tagged
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Cat.#:CDK2AP1-7628HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CDK2AP1 293 Cell Lysate
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Protein Function

CDK2AP1 has several biochemical functions, for example, DNA polymerase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK2AP1 itself. We selected most functions CDK2AP1 had, and list some proteins which have the same functions with CDK2AP1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA polymerase binding
Related Protein FANCI; PCNA; RAD51; FANCD2; SMARCA4; ACD; LONP1; HMGB1; CDK2AP1
Function protein binding
Related Protein MED24; DNAI1; ACTB; RSL24D1; TREX1; CDK20; EPB41B; SUMO3; TNNT1; PSAP

Interacting Protein

CDK2AP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK2AP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK2AP1.
MRFAP1L1; HDAC1; HDAC2; CCDC136; MTA2; MBD3