|Official Full Name||charged multivesicular body protein 2A|
|Background||CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are;components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of;surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and;cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and;regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).|
|Synonyms||CHMP2A; charged multivesicular body protein 2A; chromatin modifying protein 2A; BC 2; CHMP2; putative breast adenocarcinoma marker (32kD); VPS2; VPS2 homolog A (S. cerevisiae); VPS2A; BC2; hVps2 1; putative breast adenocarcinoma marker; Putative breast adenocarcinoma marker BC2; Vacuolar protein sorting associated protein 2 1; Vps2 1; vps2-1; hVps2-1; VPS2 homolog A; chromatin-modifying protein 2a; putative breast adenocarcinoma marker BC-2; vacuolar protein sorting-associated protein 2-1; BC-2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CHMP2A involved in several pathways and played different roles in them. We selected most pathways CHMP2A participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHMP2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Endocytosis||DNM2B; ARPC5A; ARPC4L; TGFB1; SMAP1; HLA-G; EHD1; TGFBR1B; DNM2; IGF1R|
CHMP2A has several biochemical functions, for example, phosphatidylcholine binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHMP2A itself. We selected most functions CHMP2A had, and list some proteins which have the same functions with CHMP2A. You can find most of the proteins on our site.
|phosphatidylcholine binding||CHMP2A; GPR12; RASGRP1; APOA4A; NF1; PCTP; ALDOB; APOA4B.1; CHMP3; APOA4|
|protein binding||UBR2; RSAD2; GP5; SSBP1; UBE2E1; UPF3A; MRPL23; ACCS; ELF3; FBXW2|
|protein domain specific binding||ARFIP1; DVL2; HOMER2; RUNX2; NEDD4; DDC; TNFAIP1; PLAUR; ACTN2; SHROOM2|
CHMP2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHMP2A here. Most of them are supplied by our site. Hope this information will be useful for your research of CHMP2A.
DOCK8; USP8; USP54; PCBD1; TGFB3; E2F4; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; midostaurin; Ring1; ATP6AP2; VCAM1; Rab5c; Vps4b; RAB5C