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Official Full Name cholinergic receptor, nicotinic, beta 2 (neuronal)
Background Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Synonyms Acetylcholine receptor beta 2 neural; ACHB2_HUMAN; ACHN; Acrb 2; Acrb2; b2 nAchR; Cholinergic receptor nicotinic beta 2; Cholinergic receptor nicotinic beta polypeptide 2; Cholinergic receptor nicotinic beta polypeptide 2 neuronal; CHRNB2; EFNL 3; EFNL3; nAChRB2; Neuronal acetylcholine receptor protein beta 2 chain precursor; Neuronal acetylcholine receptor protein subunit beta 2; Neuronal acetylcholine receptor subunit beta-2; Neuronal nicotinic acetylcholine receptor beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); Nicotinic beta 2 Receptor; OTTHUMP00000035374; Nicotinic beta 2 (carboxyl terminal) Receptor
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHRNB2-11217H Recombinant Human CHRNB2, His-tagged E.coli His
    Human CHRNB2-1286H Recombinant Human CHRNB2 Protein, GST-Tagged Wheat Germ GST
    Human CHRNB2-7512HCL Recombinant Human CHRNB2 293 Cell Lysate HEK293 N/A
    Rat CHRNB2-1397R Recombinant Rat CHRNB2 Protein Mammalian Cell His
    Rhesus Macaque CHRNB2-864R Recombinant Rhesus monkey CHRNB2 Protein, His-tagged Mammalian Cell His
    Chicken CHRNB2-6376C Recombinant Chicken CHRNB2 Mammalian Cell His

    CHRNB2 involved in several pathways and played different roles in them. We selected most pathways CHRNB2 participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, Cholinergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Acetylcholine Binding And Downstream Events CHRNA1; CHRNA7; CHRND; CHRNB4; CHRNA3; CHRNE; CHRNB2; CHRNA2; CHRNA5; CHRNA4
    Activation of Nicotinic Acetylcholine Receptors CHRNA3; CHRND; CHRNB2; CHRNE; CHRNA5; CHRNA2; CHRNA4; CHRNB4; CHRNA7; CHRNA1
    Cholinergic synapse PIK3CG; CREB3L2; GNG8; CHRM3; GNB2; PRKCA; GNG13; PIK3R2; KCNQ3; GNGT1
    Highly calcium permeable nicotinic acetylcholine receptors CHRNA5; CHRNA4; CHRNA1; CHRNA3; CHRNA2; CHRNB4; CHRNB2
    Highly calcium permeable postsynaptic nicotinic acetylcholine receptors CHRNA7; CHRNB2; CHRNA2; CHRNB4; CHRNA4; CHRNA1; CHRNA5; CHRNA3
    Highly sodium permeable acetylcholine nicotinic receptors CHRNA3; CHRNA4; CHRND; CHRNE; CHRNB4; CHRNB2
    Neuroactive ligand-receptor interaction GABRE; GRIA2B; GRIA3A; GRIA4A; NTSR2; NPFFR2.1; GRIA2; GRIK3; GLP2R; HTR1A
    Neuronal System AKAP5; KCNH1B; CACFD1; KCNK13B; LIN7B; GJA10; KCNK7; BZRAP1; CHRNA4; KCNJ1A.3

    CHRNB2 has several biochemical functions, for example, acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNB2 itself. We selected most functions CHRNB2 had, and list some proteins which have the same functions with CHRNB2. You can find most of the proteins on our site.

    Function Related Protein
    acetylcholine binding CHRNB1; CHRNB2; CHRNA7; CHRNA4; CHRFAM7A; ACHE; CHRM3; CHRNA3; CHRNB3
    acetylcholine receptor activity CHRNA5; CHRNB4; CHRNE; CHRNA6; CHRNB2; ANXA9; CHRNA2; CHRNA3; CHRNA7; CHRNA4
    acetylcholine-activated cation-selective channel activity CHRNA6; CHRNA4; Chrng; CHRNB2; CHRNA3; CHRNE; CHRNB3A; CHRNA5; CHRNA7; CHRNA4B
    drug binding TLR7; CHRNB4; FNTB; PDE10A; DRD1; TYMS; PDE2A; MTOR; SETD6; CYP2D6
    ligand-gated ion channel activity CHRNB4; ZACN; CNGA3; CHRNA4; ANXA6; CHRNA5; CHRNB2; Chrng; CLCA5; CHRNA3
    protein binding ZNF193; LCAT; HAND1; APPB; BUD31; KHDRBS2; ELF1; UBA2; C6; LYAR
    protein heterodimerization activity KCNB2; INHA; BNIP3L; SMC1A; PRPH; MAFG; CAV1; SOX14; ITGB1A; PEF1

    CHRNB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNB2.


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