Recombinant Full Length Human CHRNB2 Protein, GST-tagged

• Cat.No.: CHRNB2-3242HF
• Product Overview: Human CHRNB2 full-length ORF (BAG36255.1, 1 a.a. - 502 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 83.4 kDa
• Protein Length: 502 amino acids
• AA Sequence: MARRCGPVALLLGFGLLRLCSGVWG TDTEERLVEHLLDHSRYNKLIRPAT NGSELVTVQLMVSLAQLISVHEREQ IMTTNVWLTQEWEDYRLTWKPEEFD NMKKVRLPSKHIWLPDVVLYNNADG MYEVSFYSNAVVSYDGSIFWLPPAI YKSACKIEVKHFPFDQQNCTMKFRS WTYDRTEIDLVLKSEVASLDDFTPS GEWDIVALPGRRNENPDDSTYVDIT YDFIIRRKPLFYTINLIIPCVLITS LAILVFYLPSDCGEKMTLCISVLLA LTVFLLLISKIVPPTSLDVPLVGKY LMFTMVLVTFSIVTSVCVLNVHHRS PTTHTMAPWVKVVFLEKLPALLFMQ QPRHHCARQRLRLRRRQREREGAGA LFFREAPGADSCTCFVNRASVQGLA GAFGAEPAPVAGPGRSGEPCGCGLR EAVDGVRFIADHMRSEDDDQSVSED WKYVAMVIDRLFLWIFVFVCVFGTI GMFLQPLFQNYTTTTFLHSDHSAPS SK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) [ Homo sapiens ]
• Official Symbol: CHRNB2
• Synonyms: CHRNB2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); neuronal acetylcholine receptor subunit beta-2; acetylcholine receptor; nicotinic; beta 2 (neuronal); neuronal nicotinic acetylcholine receptor beta 2; acetylcholine receptor, nicotinic, beta 2 (neuronal); EFNL3; nAChRB2
• Gene ID: 1141
• mRNA Refseq: NM_000748
• Protein Refseq: NP_000739
• MIM: 118507
• UniProt ID: P17787