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Official Full Name cholinergic receptor, nicotinic, beta 4
Background Neuronal acetylcholine receptor subunit beta-4 is a protein that in humans is encoded by the CHRNB4 gene.
Synonyms neuronal acetylcholine receptor subunit beta-4; CHRNB4; OTTHUMP00000185021; neuronal nicotinic receptor beta 4 subunit; cholinergic receptor, nicotinic, beta polypeptide 4; cholinergic receptor, nicotinic, beta 4; ACHB4_HUMAN; Cholinergic receptor nicotinic beta 4; Cholinergic receptor nicotinic beta polypeptide 4; Nicotinic beta 4 Receptor
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHRNB4-1290H Recombinant Human CHRNB4 Protein, GST-Tagged Wheat Germ GST
    Human CHRNB4-7511HCL Recombinant Human CHRNB4 293 Cell Lysate HEK293 N/A
    Rat CHRNB4-1399R Recombinant Rat CHRNB4 Protein Mammalian Cell His
    Chicken CHRNB4-6382C Recombinant Chicken CHRNB4 Mammalian Cell His

    CHRNB4 involved in several pathways and played different roles in them. We selected most pathways CHRNB4 participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, Cholinergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Acetylcholine Binding And Downstream Events CHRND; CHRNB4; CHRNA3; CHRNE; CHRNA7; CHRNA5; CHRNA4; CHRNA1; CHRNA2; CHRNB2
    Activation of Nicotinic Acetylcholine Receptors CHRNA3; CHRNA4; CHRNA2; CHRNB4; CHRNA7; CHRNB2; CHRNE; CHRND; CHRNA5; CHRNA1
    Cholinergic synapse CHRNB4; CHRM4; KCNQ1; GNG3; KCNQ2; NRAS; PIK3R5; GNG5; CHRNB2; ACHE
    Highly calcium permeable nicotinic acetylcholine receptors CHRNA3; CHRNA4; CHRNB2; CHRNA5; CHRNB4; CHRNA2; CHRNA1
    Highly calcium permeable postsynaptic nicotinic acetylcholine receptors CHRNA2; CHRNA5; CHRNA3; CHRNA7; CHRNA4; CHRNB2; CHRNB4; CHRNA1
    Highly sodium permeable acetylcholine nicotinic receptors CHRNA3; CHRNB4; CHRND; CHRNE; CHRNA4; CHRNB2
    Neuroactive ligand-receptor interaction HCRTR2; CHRNA2; TAAR14D; GLRB; PRLHR2A; TAAR7F; F2RL1; HTR1B; TAAR1; GRIA4B
    Neuronal System KCNMA1; ARL6IP5A; KCNH1B; Apba1; KCNAB2B; CHRNB4; KCNN3; NSFB; KCNC1A; SLC6A12

    CHRNB4 has several biochemical functions, for example, contributes_to acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNB4 itself. We selected most functions CHRNB4 had, and list some proteins which have the same functions with CHRNB4. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to acetylcholine binding CHRNA9; CHRNA2; CHRNB4; ZACN; CHRNA1; CHRNA5; CHRNA2A; CHRNA10; CHRNB1; CHRNA6
    acetylcholine receptor activity CHRNA3; CHRNA2; CHRNA4; CHRNE; CHRNA6; CHRNA7; CHRNB4; CHRNA5; CHRNB2; ANXA9
    acetylcholine-activated cation-selective channel activity CHRNA7; CHRNB3A; CHRND; CHRNB1L; CHRNB2; Chrng; CHRNA3; CHRNE; CHRNA5; CHRNA6
    drug binding FNTB; CYP4B1; UGT1A7; MTOR; GRIK1; PDE10A; DRD4; Alb; PDE4D; PPP3CA
    ligand-gated ion channel activity CNGA3; CHRNA3; CHRNB4; GABRB1; CLCA5; P2RX2; CHRNB2; CHRNA5; TRPA1A; Chrng
    protein heterodimerization activity FZD9; HER11; SNX6; KATNA1; UGT1A6B; ZHX2; SMC4; EFHA1; HNF1A; H2AFB2

    CHRNB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNB4.

    Gelernter, J; Kranzler, HR; et al. Genome-Wide Association Study of Nicotine Dependence in American Populations: Identification of Novel Risk Loci in Both African-Americans and European-Americans. BIOLOGICAL PSYCHIATRY 77:493-503(2015).
    Sieminska, A; Jassem, E; et al. Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey. BMC PUBLIC HEALTH 15:-(2015).

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