|Official Full Name||collagen, type X, alpha 1|
|Background||This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).|
|Synonyms||COL10A1; collagen, type X, alpha 1; collagen alpha-1(X) chain; collagen X, alpha-1 polypeptide; Schmid metaphyseal chondrodysplasia<br/>|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
COL10A1 involved in several pathways and played different roles in them. We selected most pathways COL10A1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL10A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Assembly of collagen fibrils and other multimeric structures||COL1A1; CTSL1; LOXL2; COL4A6; COL3A1; COL8A2; COL8A1A; CTSL2; LOX; COL11A1B|
|Collagen biosynthesis and modifying enzymes||PCOLCE2; COL4A4; COL9A1B; COL6A2; COL5A1; TLDC2; COL9A1A; COL8A1; COL17A1; PCOLCEB|
|Collagen formation||COL10A1; COL1A2; MMP13; COL13A1; CTSL2; LOXL1; LOXL3; COL5A2; COL15A1B; ADAMTS2|
|Endochondral Ossification||MGP; KIF3A; NKX3-2; CDKN1C; COL10A1; COL2A1; NKX3.2; ADAMTS4; SOX9A; ADAMTS1|
|Extracellular matrix organization||CTSK; FURINA; TTR; BMP1B; COL17A1; FMOD; ADAMTS1; LOC100686744; ADAMTS3; COL9A1A|
|Protein digestion and absorption||CELA2B; COL15A1; ATP1A2; COL18A1; SLC9A3; COL6A4; DPP4; MEP1A; ATP1B2; XPNPEP2|
|Senescence and Autophagy||ATG7; IGFBP7; IGFBP5; IFI16; GABARAP; FKBP8; MAP1LC3C; UVRAG; IL24; ING1|
COL10A1 has several biochemical functions, for example, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL10A1 itself. We selected most functions COL10A1 had, and list some proteins which have the same functions with COL10A1. You can find most of the proteins on our site.
|metal ion binding||NOS2A; PHLPP2; PDE8A; PPM1LB; PPM1E; MMP14A; TIMM8A2; GLI1; BMP1B; ZNF143B|
|protein binding||APLF; PLEKHO1; TFF1; TRADD; CBX1; LRRC33; HIST1H2AK; STMN1; VPREB1; MYOC|
COL10A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL10A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL10A1.
BANP; UBQLN1; UBQLN1; P4HB