crabp1
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  • Official Full Name
  • cellular retinoic acid binding protein 1
  • Background
  • This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
  • Synonyms
  • CRABP1; cellular retinoic acid binding protein 1; cellular retinoic acid binding protein 1 , RBP5; cellular retinoic acid-binding protein 1; CRABP; CRABP I; CRABPI; cellular retinoic acid-binding protein I; RBP5; CRABP-I
Cat.#:CRABP1-1828HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CRABP1 Protein, GST-tagged
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Cat.#:CRABP1-11550HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP1, His-tagged
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Cat.#:CRABP1-202HTag:Fc
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP1, None tagged
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Cat.#:CRABP1-26984THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP1
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Cat.#:CRABP1-3875MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CRABP1 Protein
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Cat.#:CRABP1-1583RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CRABP1 Protein
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Cat.#:CRABP1-2253CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CRABP1
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Cat.#:CRABP1-481HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human cellular retinoic acid binding protein 1
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Cat.#:CRABP1-197HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CRABP1 lysate
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Involved Pathway

CRABP1 involved in several pathways and played different roles in them. We selected most pathways CRABP1 participated on our site, such as RA biosynthesis pathway, Signal Transduction, Signaling by Retinoic Acid, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RA biosynthesis pathway
CRABP1B; SDR16C5; CYP26A1; RDH14; ALDH8A1; AKR1C21; DHRS3; RDH10; RDH14B; ADH8A
Signal Transduction
GPR55A; GAL; IQCE; ANXA1A; GDI1; OR4D2; CDC42EP2; WDR35; ARHGEF3; RGS7
Signaling by Retinoic Acid
RDH14; RDH10; PDK2B; CRABP1B; FABP11A; ALDH8A1; PDK4; RARG; RDH14B; CRABP2B
Vitamin A and carotenoid metabolism
CRABP2; BCO2; DHRS3; RDH10; CRABP1; RBP7; RARG; RDH12

Protein Function

CRABP1 has several biochemical functions, for example, protein binding, retinal binding, retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRABP1 itself. We selected most functions CRABP1 had, and list some proteins which have the same functions with CRABP1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SLC25A10; NME2; ATXN7; MNAT1; NFS1; TGM2; LGR4; KHDRBS2; POGZ; C16orf59
Function retinal binding
Related Protein RBP7; RBP2A; CRABP2; RBP2; RBP1; RBP2B; RBP5; RBP4; RBP3; CRABP1
Function retinoic acid binding
Related Protein RARA; LCN12; CRABP2B; CRABP2A; NR2F2; CRABP2; UGT1A2; CYP26B1; UGT1A1; CRABP1A
Function retinoid binding
Related Protein CRABP1; RBP1; CRABP2; RBP4L; RBP2; PTGDS; RBP5; RBP3; LCN5
Function retinol binding
Related Protein RBP7; CRABP2; ADH7; RLBP1; RBP1; RBP5; RBP4; RBP2; CRABP1; ADH4
Function transporter activity
Related Protein NUP88; SLC4A1B; CHP1; ATP5O; SYN1; SLC13A5A; ATP5D; FLR; SLC4A2A; ASNA1

Interacting Protein

CRABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRABP1.
p27958-pro_0000037576; MPP3; TRA2A

CRABP1 Related Articles

Hattori, T; Uchida, C; et al. Distinct and Site-Specific Phosphorylation of the Retinoblastoma Protein at Serine 612 in Differentiated Cells. PLOS ONE 9:-(2014).
Leitch, VD; Dwivedi, PP; et al. Retinol-binding protein 4 downregulation during osteogenesis and its localization to non-endocytic vesicles in human cranial suture mesenchymal cells suggest a novel tissue function. HISTOCHEMISTRY AND CELL BIOLOGY 139:75-87(2013).