crmp1
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  • Official Full Name
  • cAMP responsive element binding protein 1
  • Background
  • CRMP1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • CRMP1; collapsin response mediator protein 1; DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3; dihydropyrimidinase-related protein 1; OTTHUMP00000155142; OTTHUMP00000217352; OTTHUMP00000217353; dihydropyrimidinase-like 1; unc-33-like phosphoprotein 3; dihydropyrimidinase related protein-1 CRMP1; dihydropyrimidinase related protein-1
Cat.#:CRMP1-1172HTag:His-SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRMP1 Protein, His-SUMO-tagged
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Cat.#:CRMP1-1894HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CRMP1 Protein, GST-tagged
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Cat.#:CRMP1-635HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRMP1 Protein, His-tagged
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Cat.#:CRMP1-110HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Collapsin Response Mediator Protein 1
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Cat.#:CRMP1-11585HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRMP1, GST-tagged
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Cat.#:CRMP1-26625THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRMP1
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Cat.#:CRMP1-1033RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CRMP1 Protein, His-tagged
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Cat.#:CRMP1-6065CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CRMP1
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Cat.#:CRMP1-2870ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CRMP1
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Cat.#:CRMP1-7273HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CRMP1 293 Cell Lysate
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Involved Pathway

CRMP1 involved in several pathways and played different roles in them. We selected most pathways CRMP1 participated on our site, such as Axon guidance, CRMPs in Sema3A signaling, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRMP1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
SCN2B; ANK2B; NFATC4; PLXND1; NRG2A; RASA1; RND1L; EPHB3A; DUSP7; KIF4A
CRMPs in Sema3A signaling
DPYSL3; SEMA3AA; SEMA3AB; DPYSL5A; DPYSL5B; CDK5R1B; DPYSL2B; NRP1A; SEMA3A; DPYSL2
Developmental Biology
MED15; SCN4A; DNM1; SPTA1; DRAP1; GDF1; NRP1A; NR2F2; KDR; CLTC
Semaphorin interactions
PLXNC1; CDK5R1B; DPYSL2B; CRMP1; SEMA3A; RND1L; DPYSL2; DPYSL5A; DPYSL5B; DPYSL4

Protein Function

CRMP1 has several biochemical functions, for example, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRMP1 itself. We selected most functions CRMP1 had, and list some proteins which have the same functions with CRMP1. You can find most of the proteins on our site.
Function
Related Protein
Function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Related Protein DPYSL4; DPYSL5A; DPYSL5B; DPYSL5; DPYSL2B; NAAA; BTD; DPYSL3; YDJC; CRMP1
Function protein binding
Related Protein TTC3; TAF1C; NXT2; VEGFAA; THBS2; FCER1G; TTC39B; RANGAP1; PODXL2; PTPRS

Interacting Protein

CRMP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRMP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRMP1.
VIM; DPYSL3; AP3M1; TK1; AXIN1; HTT; PSMD11; RGL2; MRPS12; NVL; Gne

CRMP1 Related Articles

Shimada, K; Ishikawa, T; et al. Collapsin response mediator protein 2 is involved in regulating breast cancer progression. BREAST CANCER 21:715-723(2014).
Bradshaw, NJ; Bader, V; et al. Aggregation of the Protein TRIOBP-1 and Its Potential Relevance to Schizophrenia. PLOS ONE 9:-(2014).