Recombinant Human CRMP1, GST-tagged

• Cat.No.: CRMP1-11585H
• Product Overview: Recombinant Human CRMP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 291-537a.a.
• Description: This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CRMP1 collapsin response mediator protein 1 [ Homo sapiens ]
• Official Symbol: CRMP1
• Synonyms: CRMP1; collapsin response mediator protein 1; dihydropyrimidinase-related protein 1; DPYSL1; DRP 1; dihydropyrimidinase-like 1; unc-33-like phosphoprotein 3; dihydropyrimidinase related protein-1; DRP1; DRP-1; CRMP-1; ULIP-3
• Gene ID: 1400
• mRNA Refseq: NM_001014809
• Protein Refseq: NP_001014809
• MIM: 602462
• UniProt ID: Q14194
• Chromosome Location: 4p16.1
• Pathway: Axon guidance, organism-specific biosystem; CRMPs in Sema3A signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem
• Function: dihydropyrimidinase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; phosphoprotein binding; protein binding