Recombinant Human CRMP1 Protein (Met1-Val250), His tagged

• Cat.No.: CRMP1-1811H
• Product Overview: Recombinant human CRMP1 (Met1-Val250) fused with His tag was expressed in E. coli.

Specification

• Description: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 26.99 kDa
• Protein Length: Met1-Val250
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: CRMP1 collapsin response mediator protein 1 [ Homo sapiens (human) ]
• Official Symbol: CRMP1
• Synonyms: CRMP1; collapsin response mediator protein 1; dihydropyrimidinase-related protein 1; DPYSL1; DRP 1; dihydropyrimidinase-like 1; unc-33-like phosphoprotein 3; dihydropyrimidinase related protein-1; DRP1; DRP-1; CRMP-1; ULIP-3
• Gene ID: 1400
• mRNA Refseq: NM_001014809
• Protein Refseq: NP_001014809
• MIM: 602462
• UniProt ID: Q14194