Recombinant Full Length Human CRMP1 Protein, C-Flag-tagged

• Cat.No.: CRMP1-524HFL
• Product Overview: Recombinant Full Length Human CRMP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 62 kDa
• AA Sequence: MSYQGKKSIPHITSDRLLIKGGRII NDDQSLYADVYLEDGLIKQIGENLI VPGGVKTIEANGRMVIPGGI DVNTYLQKPSQGMTAADDFFQGTRA ALVGGTTMIIDHVVPEPGSSLLTSF EKWHEAADTKSCCDYSLHVD ITSWYDGVREELEVLVQDKGVNSFQ VYMAYKDVYQMSDSQLYEAFTFLKG LGAVILVHAENGDLIAQEQK RILEMGITGPEGHALSRPEELEAEA VFRAITIAGRINCPVYITKVMSKSA ADIIALARKKGPLVFGEPIA ASLGTDGTHYWSKNWAKAAAFVTSP PLSPDPTTPDYLTSLLACGDLQVTG SGHCPYSTAQKAVGKDNFTL IPEGVNGIEERMTVVWDKAVATGKM DENQFVAVTSTNAAKIFNLYPRKGR IAVGSDADVVIWDPDKLKTI TAKSHKSAVEYNIFEGMECHGSPLV VISQGKIVFEDGNINVNKGMGRFIP RKAFPEHLYQRVKIRNKVFG LQGVSRGMYDGPVYEVPATPKYATP APSAKSSPSKHQPPPIRNLHQSNFS LSGAQIDDNNPRRTGHRIVA
  PPGGRSNITSLGTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CRMP1 collapsin response mediator protein 1 [ Homo sapiens (human) ]
• Official Symbol: CRMP1
• Synonyms: DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3
• Gene ID: 1400
• mRNA Refseq: NM_001313.5
• Protein Refseq: NP_001304.1
• MIM: 602462
• UniProt ID: Q14194