This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
CTAG2; cancer/testis antigen 2; CAMEL; cancer/testis antigen family 6; member 2a; member 2b; CT6.2a; CT6.2b; CTL recognized antigen on melanoma; ESO2; LAGE 1; LAGE 1a; LAGE 1a protein; LAGE 1b; LAGE1; MGC3803; MGC138724; Autoimmunogenic cancer/testis antigen NY ESO 2; Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 6.2; CT 2; CT2; CT6.2; CTAG 2; CTAG2_HUMAN; ESO 2; L antigen family member 1; LAGE 2b; LAGE-1; LAGE2b; LAGE-1a protein; OTTHUMP00000026043; OTTHUMP00000026044; CTL-recognized antigen on melanoma; cancer/testis antigen family 6, member 2a; cancer/testis antigen family 6, member 2b; autoim
CTAG2 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTAG2 itself. We selected most functions CTAG2 had, and list some proteins which have the same functions with CTAG2. You can find most of the proteins on our site.
Related Protein CEP19; BCL7A; PANE1; NAT14; FADS3; SLAIN1; C9orf16; TVP23B; IGLON5; TMEM238
Function protein binding
Related Protein SULT4A1; HHIP; CNTNAP4; CEBPA; ZNF502; MICAL1; CENPH; GM5506; NSMCE2; ITGB1BP1
CTAG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTAG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTAG2.