CTSO Protein, cathepsin O


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Official Full Name cathepsin O
Background The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase.
Synonyms CTSO; cathepsin O; CTSO1; OTTHUMP00000220879
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CTSO-1103H Recombinant Human CTSO protein, His & T7-tagged E.coli His/T7
    Human CTSO-2117H Recombinant Human CTSO Protein, GST-tagged Wheat Germ GST
    Human CTSO-7190HCL Recombinant Human CTSO 293 Cell Lysate HEK293 N/A
    Mouse CTSO-4059M Recombinant Mouse CTSO Protein Mammalian Cell His
    Chicken CTSO-2801C Recombinant Chicken CTSO Mammalian Cell His

    CTSO involved in several pathways and played different roles in them. We selected most pathways CTSO participated on our site, such as Adaptive Immune System, Immune System, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System DCTN2; STUB1; UFL1; FBXO3; DNM2; FRS2B; SIGLEC12; KIF22; KIR2DS2; UBE2U
    Immune System MGC174155; CASP4; IFIT14; TREM1; LRR1; IRF9; RAET1E; CR1; DEFB104A; TNFRSF13C
    Lysosome SCARB2; ACP2; ATP6V0A1; SLC11A1; CTSBA; ARSB; AP3B2; GALCB; SLC11A2; IGF2R
    MHC class II antigen presentation CTS7; MGC174857; KIF26A; KIF22; DCTN6; CTSO; MGC174155; CTSC; KIF15; DYNC1I1

    CTSO has several biochemical functions, for example, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSO itself. We selected most functions CTSO had, and list some proteins which have the same functions with CTSO. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase activity USP47; CTSBA; USP37; USP2; USP22; CTSSA; USP13; CTSO; CASP6L2; USP16

    CTSO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSO here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSO.


    Pennypacker, BL; Chen, CM; et al. Inhibition of Cathepsin K Increases Modeling-Based Bone Formation, and Improves Cortical Dimension and Strength in Adult Ovariectomized Monkeys. JOURNAL OF BONE AND MINERAL RESEARCH 29:1847-1858(2014).
    Lerner, I; Zcharia, E; et al. Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice. CELLULAR AND MOLECULAR LIFE SCIENCES 71:2347-2357(2014).

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