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CTSO

Official Full Name

cathepsin O
Overview

The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase.
Synonyms

CTSO; cathepsin O; CTSO1; OTTHUMP00000220879;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
His|T7
MBP
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CTSO-1103H	Recombinant Human CTSO protein, His & T7-tagged	E.coli	His/T7	Arg111~Ser317 (Accession # P43234)	Inquiry
Human	CTSO-2117H	Recombinant Human CTSO Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CTSO-7190HCL	Recombinant Human CTSO 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CTSO-5005H	Recombinant Human CTSO protein, His&Myc-tagged	HEK293	His&Myc	108-321aa	Inquiry
Human	CTSO-2213H	Recombinant Human CTSO protein, MBP&His-tagged	Insect Cell	MBP&His	108-321aa	Inquiry
Human	CTSO-2765H	Recombinant Human CTSO protein, His&Myc-tagged	E.coli	His&Myc	108-321aa	Inquiry
Human	CTSO-2362HF	Recombinant Full Length Human CTSO Protein, GST-tagged	In Vitro Cell Free System	GST	24-321 amino acids	Inquiry
Mouse	CTSO-4059M	Recombinant Mouse CTSO Protein	Mammalian Cell	His		Inquiry
Mouse	CTSO-2072M	Recombinant Mouse CTSO Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CTSO-2072M-B	Recombinant Mouse CTSO Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	CTSO-2801C	Recombinant Chicken CTSO	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CTSO Related Articles
CTSO Related Research Area

CTSO involved in several pathways and played different roles in them. We selected most pathways CTSO participated on our site, such as Adaptive Immune System, Immune System, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	KIF4A;ASB13;FGF18B;SH3RF1;OSCAR;PJA2;LILRB5;LRSAM1;FCGR1B
Immune System	BTR06;DEFB4A;AP1M2;BTR12;KLHL21;PRLRB;GM11711;PELI2;ARIH1L
Lysosome	NPC1;SLC11A2;GALCA;CD164;CD68;LGMN;ABCB9;Ctsl;ENTPD4
MHC class II antigen presentation	ACTR1B;FAM49BA;CTSO;CTSE;CTS7;KIF22;KIF26A;CTSC;OSBPL1A

CTSO has several biochemical functions, for example, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSO itself. We selected most functions CTSO had, and list some proteins which have the same functions with CTSO. You can find most of the proteins on our site.

Function	Related Protein
cysteine-type endopeptidase activity	CTSS;CTSZ;CTS7;USP43A;CASP8L1;CASPA;USP3;USP24;CTLA2B

CTSO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSO here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSO.

hldE

Pennypacker, BL; Chen, CM; et al. Inhibition of Cathepsin K Increases Modeling-Based Bone Formation, and Improves Cortical Dimension and Strength in Adult Ovariectomized Monkeys. JOURNAL OF BONE AND MINERAL RESEARCH 29:1847-1858(2014).

Lerner, I; Zcharia, E; et al. Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice. CELLULAR AND MOLECULAR LIFE SCIENCES 71:2347-2357(2014).

Lysosomal Enzymes