|Official Full Name||chaperonin containing TCP1, subunit 2 (beta)|
|Background||CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized|
|Synonyms||CCT2; chaperonin containing TCP1, subunit 2 (beta); T-complex protein 1 subunit beta; Cctb; T-complex protein 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing t-complex polypeptide 1, beta subunit; 99D|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
Cct2 involved in several pathways and played different roles in them. We selected most pathways Cct2 participated on our site, such as Assembly of the primary cilium, Association of TriC/CCT with target proteins during biosynthesis, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cct2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Assembly of the primary cilium||IFT22; FBF1; TTBK2; PROL1; IFT172; NDE1; CCT4; PCM1; CEP72; CEP164|
|Association of TriC/CCT with target proteins during biosynthesis||TCP1; FBXW2; CCT5; NOP56; CCT4; CCT3; CCT7; FBXW9; CCT2; FBXL5|
|BBSome-mediated cargo-targeting to cilium||BBS7; SSTR3; TTC8; BBS2; PROL1; CCT5; BBS1; BBS12; BBS5; BBS9|
|Cargo trafficking to the periciliary membrane||BBS10; UNC119B; TTC8; PKD2; CNGA5; BBS1; RHOL; BBS7; EXOC1; CYS1|
|Chaperonin-mediated protein folding||CCT6A; CCT4; CCT2; TCP1; TUBB4A; CCT7; FBXW5; PFDN2; CCT5; PFDN1|
|Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding||CCT6A; TUBA3D; PFDN2; CCT7; PFDN1; PFDN4; CCT3; PFDN6; TUBB4A; CCT5|
|Folding of actin by CCT/TriC||CCT6A; TCP1; CCT4; CCT3; CCT2; CCT7; CCT8; CCT5|
|Formation of tubulin folding intermediates by CCT/TriC||CCT2; CCT7; TUBB4B; CCT8; CCT6A; TUBB4A; CCT4; TUBA1B; CCT5; CCT3|
Cct2 has several biochemical functions, for example, ATP binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cct2 itself. We selected most functions Cct2 had, and list some proteins which have the same functions with Cct2. You can find most of the proteins on our site.
|ATP binding||MYH4; CHD2; EHD2; SRR; MAPK14A; NLRP12; P2RY1; FIGNL2; CLK4B; SMC3|
|protein binding||PPP1R16B; CSPP1; CLEC16A; CDH15; C9orf142; NKX2; CNOT10; GHRHR; ARFRP1; SNAP29|
|ubiquitin protein ligase binding||FANCL; UBE2A; EGR2; UBE2NB; EGFR; TRAF3; RNF34; ANKRD32; MDM2; UBE2W|
|unfolded protein binding||HSP90AA1.1; PFDN6; APCS; CALR; HSPA5; RUVBL2; CCT2; ERO1LB; LMAN1; DNAJA2L|
Cct2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cct2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cct2.
PPP2CA; PPP4C; PPP2CB; STRN3; BBS7; WRAP53