Recombinant Human CCT2 Protein (2-535 aa), His-tagged

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Recombinant Human CCT2 Protein (2-535 aa), His-tagged

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Cat.No. : CCT2-1742H
Product Overview : Recombinant Human CCT2 Protein (2-535 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.
Description : Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 59.4 kDa
Protein length : 2-535 aa
AA Sequence : ASLSLAPVNI FKAGADEERA ETARLTSFIG AIAIGDLVKS TLGPKGMDKI LLSSGRDASL MVTNDGATIL KNIGVDNPAA KVLVDMSRVQ DDEVGDGTTS VTVLAAELLR EAESLIAKKI HPQTIIAGWR EATKAAREAL LSSAVDHGSD EVKFRQDLMN IAGTTLSSKL LTHHKDHFTK LAVEAVLRLK GSGNLEAIHI IKKLGGSLAD SYLDEGFLLD KKIGVNQPKR IENAKILIAN TGMDTDKIKI FGSRVRVDST AKVAEIEHAE KEKMKEKVER ILKHGINCFI NRQLIYNYPE QLFGAAGVMA IEHADFAGVE RLALVTGGEI ASTFDHPELV KLGSCKLIEE VMIGEDKLIH FSGVALGEAC TIVLRGATQQ ILDEAERSLH DALCVLAQTV KDSRTVYGGG CSEMLMAHAV TQLANRTPGK EAVAMESYAK ALRMLPTIIA DNAGYDSADL VAQLRAAHSE GNTTAGLDMR EGTIGDMAIL GITESFQVKR QVLLSAAEAA EVILRVDNII KAAPRKRVPD HHPC
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : CCT2 chaperonin containing TCP1, subunit 2 (beta) [ Homo sapiens ]
Official Symbol : CCT2
Synonyms : CCT2; Cctb; CCTB; 99D8.1; PRO1633; CCT-beta; TCP-1-beta; MGC142074; MGC142076;
Gene ID : 10576
mRNA Refseq : NM_001198842
Protein Refseq : NP_001185771
MIM : 605139
UniProt ID : P78371

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