Recombinant Human CCT2 Protein, GST-Tagged

• Cat.No.: CCT2-0709H
• Product Overview: Human CCT2 full-length ORF (NP_006422.1, 1 a.a. - 535 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.9 kDa
• AA Sequence: MASLSLAPVNIFKAGADEERAETAR LTSFIGAIAIGDLVKSTLGPKGMDK ILLSSGRDASLMVTNDGATILKNIG VDNPAAKVLVDMSRVQDDEVGDGTT SVTVLAAELLREAESLIAKKIHPQT IIAGWREATKAAREALLSSAVDHGS DEVKFRQDLMNIAGTTLSSKLLTHH KDHFTKLAVEAVLRLKGSGNLEAIH IIKKLGGSLADSYLDEGFLLDKKIG VNQPKRIENAKILIANTGMDTDKIK IFGSRVRVDSTAKVAEIEHAEKEKM KEKVERILKHGINCFINRQLIYNYP EQLFGAAGVMAIEHADFAGVERLAL VTGGEIASTFDHPELVKLGSCKLIE EVMIGEDKLIHFSGVALGEACTIVL RGATQQILDEAERSLHDALCVLAQT VKDSRTVYGGGCSEMLMAHAVTQLA NRTPGKEAVAMESYAKALKMLPTII ADNAGYDSADLVAQLRAAHSEGNTT AGLDMREGTIGDMAILGITESFQVK RQVLLSAAEAAEVILRVDNIIKAAP RKRVPDHHPC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCT2 chaperonin containing TCP1, subunit 2 (beta) [ Homo sapiens ]
• Official Symbol: CCT2
• Synonyms: CCT2; chaperonin containing TCP1, subunit 2 (beta); T-complex protein 1 subunit beta; Cctb; T-complex protein 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing t-complex polypeptide 1, beta subunit; CCTB; 99D8.1; PRO1633; CCT-beta; TCP-1-beta; MGC142074; MGC142076
• Gene ID: 10576
• mRNA Refseq: NM_001198842
• Protein Refseq: NP_001185771
• MIM: 605139
• UniProt ID: P78371