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Official Full Name cardiotrophin 2
Background Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-a component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human Neuropoietin gene has evolved toward a pseudogene, suggesting that the alternative signaling via CNTF is an effective compensatory pathway.
Synonyms NP; Gm494
    • Species :
    • Mouse
    • Source :
    • E. coli
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Ctf2-2357M Recombinant Mouse Ctf2 Protein E. coli
    Mouse Ctf2-2068M Recombinant Mouse Ctf2 protein E.coli N/A
    Mouse CTF2-4021M Recombinant Mouse CTF2 Protein Mammalian Cell His
    Mouse Ctf2-952M Recombinant Mouse Cardiotrophin 2 E.coli N/A

    Ctf2 involved in several pathways and played different roles in them. We selected most pathways Ctf2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Ctf2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Ctf2 has several biochemical functions, for example, ciliary neurotrophic factor receptor binding, cytokine activity, leukemia inhibitory factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ctf2 itself. We selected most functions Ctf2 had, and list some proteins which have the same functions with Ctf2. You can find most of the proteins on our site.

    Function Related Protein
    ciliary neurotrophic factor receptor binding LIFR; Ctf2; CLCF1; IL6ST; CNTF
    cytokine activity TNFSF14; SCGB3A1; INHBB; IFNB; IL17A; CSF1B; TNFSF15; BMP5; IL17A/F3; TNFSF10
    leukemia inhibitory factor receptor binding LIF; CTF1; Ctf2

    Ctf2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ctf2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ctf2.

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