DCAF7
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Official Full Name
DDB1 and CUL4 associated factor 7
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Overview
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. -
Synonyms
DCAF7; DDB1 and CUL4 associated factor 7; WD repeat domain 68 , WDR68; DDB1- and CUL4-associated factor 7; HAN11; human anthocyanin; seven WD repeat protein of the AN11 family 1; SWAN 1; AN11; DCAF7_HUMAN; WD repeat domain 68; WD repeat protein An11 homolog; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WDR68; WD-repeat protein; seven-WD-repeat protein of the AN11 family-1; SWAN-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Zebrafish
- E.coli
- HEK293
- Human
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- GST
- His
- Strep
- SUMO
- N/A
- No tag
- T7
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | DCAF7-3624H | Recombinant Human DCAF7, His-tagged | Human | His | ||
Human | DCAF7-30698TH | Recombinant Human DCAF7, His-tagged | E.coli | His | 277 amino acids | |
Human | DCAF7-3012H | Recombinant Human DDB1 And CUL4 Associated Factor 7, T7-tagged | E.coli | T7 | ||
Human | DCAF7-4565H | Recombinant Human DCAF7 Protein, GST-tagged | Wheat Germ | GST | ||
Human | DCAF7-7055HCL | Recombinant Human DCAF7 293 Cell Lysate | HEK293 | N/A | ||
Human | DCAF7-3456HF | Recombinant Full Length Human DCAF7 Protein, GST-tagged | In Vitro Cell Free System | GST | 342 amino acids | |
Human | DCAF7-3761H | Recombinant Human DCAF7 protein, His-SUMO-tagged | E.coli | His-SUMO | 1-342aa | |
Human | DCAF7-0582H | Recombinant Human DCAF7 Protein (S2-V342), Tag Free | Insect Cell | No tag | S2-V342 | |
Human | DCAF7-4210H | Recombinant Human DCAF7 protein, His-tagged | E.coli | His | 1-342aa | |
Human | DCAF7-0583H | Recombinant Human DCAF7 Protein (S2-V342), His/Strep tagged | Insect Cell | His/Strep | S2-V342 | |
Zebrafish | DCAF7-10423Z | Recombinant Zebrafish DCAF7 | Mammalian Cell | His | ||
Chicken | DCAF7-3543C | Recombinant Chicken DCAF7 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
DCAF7 involved in several pathways and played different roles in them. We selected most pathways DCAF7 participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCAF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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TNF-alpha/NF-kB Signaling Pathway | USP2;PDCD2;FAF1;PPP1R13L;MARK2;DAP;NR2C2;SMARCE1;TRAIP |
DCAF7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCAF7 itself. We selected most functions DCAF7 had, and list some proteins which have the same functions with DCAF7. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | ANKMY2;GZMB;RPGR;TGFB2;LRFN2;ELF4;SPI1;MT1X;PRPF4B |
DCAF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCAF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of DCAF7.
MAP3K1; HIPK2; DYRK1A
- Q&As
- Reviews
Q&As (5)
Ask a questionDCAF7 protein has been implicated in promoting drug resistance in cancer cells by affecting DNA repair pathways, making it an important factor in cancer treatment resistance.
While specific genetic alterations in the DCAF7 gene have not been extensively studied, it is possible that mutations or dysregulation of the gene may contribute to cancer susceptibility.
Research has suggested that DCAF7 protein may be involved in the development of various types of cancer, including breast, ovarian, and colorectal cancer.
The expression of DCAF7 protein can be assessed using immunohistochemistry or molecular techniques, which may provide valuable information for cancer prognosis and treatment planning.
Targeting DCAF7 protein may have implications for personalized cancer therapy by exploiting specific vulnerabilities in cancer cells related to DNA repair mechanisms.
Customer Reviews (3)
Write a reviewThe DCAF7 protein is a top-quality product that is sure to fulfill my experimental requirements.
It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.
the ease of use and compatibility of the DCAF7 protein with various techniques further enhances its appeal.
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