ddx4
Share
  • Official Full Name
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
  • Background
  • DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells. This enzyme is specific to germ cells and is necessary for germ cell development. Mouse DDX4 was shown to interact with Dicer suggesting a role in microRNA-medi
  • Synonyms
  • DDX4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 4; probable ATP-dependent RNA helicase DDX4; VASA; vasa homolog; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074
Cat.#:DDX4-2486HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DDX4 Protein, GST-tagged
+Inquiry
Cat.#:DDX4-468HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human DDX4 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:DDX4-11904HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DDX4, GST-tagged
+Inquiry
Cat.#:DDX4-1821RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DDX4 Protein
+Inquiry
Cat.#:DDX4-457CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DDX4 Protein, His-tagged
+Inquiry
Cat.#:DDX4-1218RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DDX4 Protein, His-tagged
+Inquiry
Cat.#:DDX4-6273CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DDX4
+Inquiry
Cat.#:DDX4-8685ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DDX4
+Inquiry
Cat.#:DDX4-7006HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DDX4 293 Cell Lysate
+Inquiry

Involved Pathway

DDX4 involved in several pathways and played different roles in them. We selected most pathways DDX4 participated on our site, such as Gene Expression, Gene Silencing by RNA, PIWI-interacting RNA (piRNA) biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
ZNF285A; FKBP6; ZNF184; CCAR1; BRF1; TAF1L; WHSC2; CSTF3; ZNF19; HIPK1
Gene Silencing by RNA
DPY19L2; BARHL1; DDX4; TARBP2; TSN; ASZ1; PIWIL4; AGO3B; TSNAX; MYBL1
PIWI-interacting RNA (piRNA) biogenesis
PLD6; FKBP6; PIWIL4; DDX4; HENMT1; MAEL; TDRD1; ASZ1; MYBL1

Protein Function

DDX4 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX4 itself. We selected most functions DDX4 had, and list some proteins which have the same functions with DDX4. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DCAKD; GLUD1; DNA2; MAP2K7; LATS1; MKNK2; P2RY4; CHD7; NME7; ZAK
Function ATP-dependent RNA helicase activity
Related Protein DDX23; DDX21; DDX17; DDX39A; DHX15; EIF4A2; DHX37; DDX19A; YTHDC2; PL10
Function nucleic acid binding
Related Protein PLAGL2; SPRN; PAN2; GPATCH2; CMTR1; BCL11AA; ZSCAN2; ZNF281B; CPEB1B; Akap17b

Interacting Protein

DDX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX4.
SRC; N; USE1