dkk4
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  • Official Full Name
  • dickkopf homolog 4
  • Background
  • This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.
  • Synonyms
  • DKK4; dickkopf homolog 4 (Xenopus laevis); dickkopf (Xenopus laevis) homolog 4; dickkopf-related protein 4; hDkk-4; dickkopf-4; DKK-4; MGC129562; MGC129563
Cat.#:DKK4-2668HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DKK4 Protein, GST-tagged
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Cat.#:Dkk4-404MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Dickkopf Homolog 4 (Xenopus laevis), His-tagged
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Cat.#:DKK4-1522HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DKK4 protein, His & T7-tagged
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Cat.#:DKK4-681HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human DKK4 Protein, His-tagged
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Cat.#:DKK4-78HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human DKK4, His-tagged
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Cat.#:Dkk4-1523MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dkk4 protein, His & GST-tagged
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Cat.#:DKK4-4612MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DKK4 Protein
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Cat.#:DKK4-6915HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DKK4 293 Cell Lysate
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Involved Pathway

DKK4 involved in several pathways and played different roles in them. We selected most pathways DKK4 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DKK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Wnt signaling pathway
RBX1; CTNNBIP1; FOSL1A; TCF7L1A; DKK2; PRICKLE2B; SFRP1A; WIF1; WNT2; SFRP2

Protein Function

DKK4 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DKK4 itself. We selected most functions DKK4 had, and list some proteins which have the same functions with DKK4. You can find most of the proteins on our site.
Function
Related Protein
Function molecular_function
Related Protein GLIPR1B; SKINT5; ADAMTS16; FMN2; INO80C; LRRC6; RAD21L; TSPAN3; TMEM131; SPON2B

DKK4 Related Articles

Hong, FS; Hong, J; et al. Chronic Exposure to Nanoparticulate TiO2 Causes Renal Fibrosis Involving Activation of the Wnt Pathway in Mouse Kidney. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63:1639-1647(2015).
Schon, S; Flierman, I; et al. beta-catenin regulates NF-kappa B activity via TNFRSF19 in colorectal cancer cells. INTERNATIONAL JOURNAL OF CANCER 135:1800-1811(2014).