DLST
-
Official Full Name
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
-
Overview
alpha-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in mitochondria. Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex. Mutations in the DLST gene may be responsible for the familial Alzheime -
Synonyms
DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); DLTS; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; E2K; OGDC-E2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cells
- Mammalian Cell
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- DLST Related Articles
DLST involved in several pathways and played different roles in them. We selected most pathways DLST participated on our site, such as 2-oxoglutarate decarboxylation to succinyl-CoA, Biosynthesis of antibiotics, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLST were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| 2-oxoglutarate decarboxylation to succinyl-CoA | DLST;DLD |
| Biosynthesis of antibiotics | DAO;DBT;AGXT;NME6;GALM;DAO1;GPR19;SDS;ACAA2 |
| Carbon metabolism | PKMA;SDHD;SUCLG2;GPIB;ALDOA;PFKP;ADH5;ANI_1_2390104;PKM |
| Citrate cycle (TCA cycle) | IDH2;IDH3B;ACLYA;PC;PDHA2;PDHA1A;SDHB;SDHA;IDH3A |
| Citric acid cycle (TCA cycle) | DLST;CS |
| Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism | UROC1;AFMID;SLC25A21;DLST;AMDHD1;IDO2;CRYM;PCBD1;FTCD |
| Lysine catabolism | CRYM;SLC25A21;DLST |
| Lysine degradation | SETDB1B;HYKK.2;SETD7;WBP7;SETD1BA;PLOD1A;SUV39H1;EHMT1;OGDH |
DLST has several biochemical functions, for example, chaperone binding, dihydrolipoyllysine-residue succinyltransferase activity, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLST itself. We selected most functions DLST had, and list some proteins which have the same functions with DLST. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chaperone binding | CDC37;TSACC;PIH1D3;GRPEL2;DNAJA2L;CDC37L1;USP13;TIMM10;BAX |
| dihydrolipoyllysine-residue succinyltransferase activity | |
| heat shock protein binding | SSUH2RS1;NFKBIA;HSPA6;DMPK;APAF1;FKBP5;DNAJA3;HSPA9;DNAJA2L |
DLST has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLST here. Most of them are supplied by our site. Hope this information will be useful for your research of DLST.
IKBKE; NDRG1; USP13; UIMC1; ARIH2; PAK4; UMPS; PFN2; NAP1L1; ZBTB16; FLII; TUBB2A; q81z98_bacan; RUSC2; DLG5; SCFD1; CCDC86; ZHX1; N; 15-deoxy-delta(12,14
- Q&As
- Reviews
Ask a Question for All DLST Products
Required fields are marked with *
My Review for All DLST Products
Required fields are marked with *
