Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

EED

  • Official Full Name

    embryonic ectoderm development

  • Overview

    This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    EED; embryonic ectoderm development; HEED; WAIT1; polycomb protein EED; WD protein associating with integrin cytoplasmic tails 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Others
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EED-6921H Recombinant Human EED, His & GST tagged Insect Cell His/GST
Human EED-7643H Recombinant Human EED, His-tagged E.coli N/A 1-441aa
Human EED-3063H Recombinant Human EED Protein, GST-tagged Wheat Germ GST
Human EED-316H Recombinant Human EED protein, His-tagged E.coli His
Human EED-775H Recombinant Human EED Mammalian Cell His
Human EED-531HCL Recombinant Human EED cell lysate Insect Cell N/A
Human EED-4291H Recombinant Human EED Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EED-410H Recombinant Human EED Protein, His-tagged E.coli His Asp142~Arg441
Human EED-2833H Recombinant Human EED Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EED-1473H Recombinant Human EED Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EED-2833H-B Recombinant Human EED Protein Pre-coupled Magnetic Beads HEK293
Human EED-1207H Recombinant Human EED Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EED-4204HF Recombinant Full Length Human EED Protein, GST-tagged In Vitro Cell Free System GST 441 amino acids
Mouse EED-4997M Recombinant Mouse EED Protein Mammalian Cell His
Mouse EED-2644M Recombinant Mouse EED Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Eed-2732M Recombinant Mouse Eed Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EED-2644M-B Recombinant Mouse EED Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EED-1381R Recombinant Rhesus monkey EED Protein, His-tagged Mammalian Cell His
Rhesus Macaque EED-1206R-B Recombinant Rhesus Macaque EED Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EED-1206R Recombinant Rhesus Macaque EED Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EED-2513Z Recombinant Zebrafish EED Mammalian Cell His
Chicken EED-3027C Recombinant Chicken EED Mammalian Cell His
CBCRY07 Embryonic Ectoderm Development E.coli N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EED Related Articles

EED involved in several pathways and played different roles in them. We selected most pathways EED participated on our site, such as Cellular Senescence, Cellular responses to stress, Chromatin modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with EED were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular SenescenceHIST4H4;CDKN2B;CBX6;CBX8B;CBX6A;HMGA1;MAPKAPK2B;SUZ12;RBBP7
Cellular responses to stressPOT1A;NUP50;LAMTOR2;KIAA1967;MAP1LC3C;ULK1A;HIST1H1E;IGFBP7;PHC2
Chromatin modifying enzymesKDM6AL;KAT8;ARID5B;RBBP5;COPRS;SUZ12;MBIP;SAP30;PADI3
Chromatin organizationKAT8;SMARCB1;KANSL3;SMARCC1;SMARCB1A;SMARCA4;SUZ12A;ING5A;SMARCB1B
Epigenetic regulation of gene expressionRBB4L;SAP30L;SUDS3;TAF1C;EED;CD3EAP;H3F3B.1;TAF1B;SUZ12
Gene ExpressionPRDX2;C14orf166;RRP8;NR1D2;SCO1;ZNF23;LAGE3;ZNF706;TPRKB
Oxidative Stress Induced SenescenceCBX8A;SUZ12;CBX6A;EED;CBX8B;TNIK;SCMH1;PHC2;BMI1B
PKMTs methylate histone lysinesSETD3;PRDM16;SUZ12B;EHMT2;SUZ12;ATF7IP;ASH2L;EED;SMYD2

EED has several biochemical functions, for example, chromatin binding, histone methyltransferase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EED itself. We selected most functions EED had, and list some proteins which have the same functions with EED. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingFABP1;HMGB2B;IFT74;MORF4L1;SVEP1;PKN1;HMGB3B;MPO;PATZ1
histone methyltransferase activitySUV39H1;SUZ12;PRMT6;CARM1;PRMT2;EED;PRDM13;EZH2;PRMT1
identical protein bindingIK;CHMP4B;PYCARD;AMOTL2;GM5077;UBQLN4;CEACAM5;EIF2AK3;KCTD17
protein bindingCMTM5;SAV1;UNC119B;TSHR;NUPL1;CCS;NUDT4;ICAM3;ELMOD3

EED has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EED here. Most of them are supplied by our site. Hope this information will be useful for your research of EED.

EZH2; DNMT3B; DNMT1; PINK1

Momen, SE; Jorizzo, J; et al. Erythema elevatum diutinum: a review of presentation and treatment. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 28:1594-1602(2014).
Andabaka, T; Nickerson, JW; et al. Monoclonal antibody for reducing the risk of respiratory syncytial virus infection in children. COCHRANE DATABASE OF SYSTEMATIC REVIEWS :-(2013).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
What is the impact of EED dysregulation on the development of cancer, especially in terms of epigenetic alterations? 08/18/2022

Dysregulation of EED can lead to cancer, largely through epigenetic alterations and disrupted gene regulation.

How does EED contribute to the maintenance of pluripotency and self-renewal in stem cells? 04/26/2022

EED helps maintain stem cell pluripotency and self-renewal capabilities, crucial for embryonic development.

How does EED interact with the Polycomb repressive complex 2 (PRC2) in chromatin remodeling? 05/05/2021

EED works with PRC2 in chromatin remodeling, influencing gene silencing and cellular identity.

How do alterations in EED expression or function affect developmental disorders and congenital anomalies? 10/26/2020

Changes in EED function impact developmental processes, potentially leading to congenital anomalies and disorders.

How does EED regulate epigenetic modifications, particularly histone methylation, in gene expression? 10/18/2020

EED regulates gene expression by modulating histone methylation, affecting epigenetic landscapes.

What role does EED play in the development and differentiation of embryonic stem cells? 06/28/2020

EED is essential in embryonic stem cell development, guiding differentiation processes.

What are the mechanisms by which EED influences cellular aging and senescence? 01/25/2019

EED affects cellular aging and senescence, playing a role in age-related epigenetic changes.

Customer Reviews (3)

Write a review
Reviews
12/25/2021

    Precise protein quantification, ensures data accuracy in our experiments.

    07/03/2020

      Dependable peptide synthesis, accelerates our projects effectively.

      03/02/2020

        Timely antibody validation, a valuable asset for our lab.

        Ask a Question for All EED Products

        Required fields are marked with *

        My Review for All EED Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends