| Description : |
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
45.3 kDa |
| AA Sequence : |
MSEREVSTAPAGTDMPAAKKQKLSS DENSNPDLSGDENDDAVSIESGTNT ERPDTPTNTPNAPGRKSWGKGKWKS KKCKYSFKCVNSLKEDHNQPLFGVQ FNWHSKEGDPLVFATVGSNRVTLYE CHSQGEIRLLQSYVDADADENFYTC AWTYDSNTSHPLLAVAGSRGIIRII NPITMQCIKHYVGHGNAINELKFHP RDPNLLLSVSKDHALRLWNIQTDTL VAIFGGVEGHRDEVLSADYDLLGEK IMSCGMDHSLKLWRINSKRMMNAIK ESYDYNPNKTNRPFISQKIHFPDFS TRDIHRNYVDCVRWLGDLILSKSCE NAIVCWKPGKMEDDIDKIKPSESNV TILGRFDYSQCDIWYMRFSMDFWQK MLALGNQVGKLYVWDLEVEDPHKAK TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
