Recombinant Human EED Protein, GST-tagged

• Cat.No.: EED-3063H
• Product Overview: Human EED full-length ORF ( NP_003788.2, 1 a.a. - 441 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.6 kDa
• AA Sequence: MSEREVSTAPAGTDMPAAKKQKLSS DENSNPDLSGDENDDAVSIESGTNT ERPDTPTNTPNAPGRKSWGKGKWKS KKCKYSFKCVNSLKEDHNQPLFGVQ FNWHSKEGDPLVFATVGSNRVTLYE CHSQGEIRLLQSYVDADADENFYTC AWTYDSNTSHPLLAVAGSRGIIRII NPITMQCIKHYVGHGNAINELKFHP RDPNLLLSVSKDHALRLWNIQTDTL VAIFGGVEGHRDEVLSADYDLLGEK IMSCGMDHSLKLWRINSKRMMNAIK ESYDYNPNKTNRPFISQKIHFPDFS TRDIHRNYVDCVRWLGDLILSKSCE NAIVCWKPGKMEDDIDKIKPSESNV TILGRFDYSQCDIWYMRFSMDFWQK MLALGNQVGKLYVWDLEVEDPHKAK CTTLTHHKCGAAIRQTSFSRDSSIL IAVCDDASIWRWDRLR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EED embryonic ectoderm development [ Homo sapiens ]
• Official Symbol: EED
• Synonyms: EED; embryonic ectoderm development; polycomb protein EED; HEED; WAIT 1; WD protein associating with integrin cytoplasmic tails 1; WAIT1
• Gene ID: 8726
• mRNA Refseq: NM_003797
• Protein Refseq: NP_003788
• MIM: 605984
• UniProt ID: O75530