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Efnb2

  • Official Full Name

    Ephrin-B2

  • Overview

    Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
  • Synonyms

    EPHB2; EPH receptor B2; DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; MGC87492; ephrin type-B receptor 2; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; EphB2; EC=2.7.10.1; Developmentally-regulated Eph-related tyrosine kinase; CAPB; PCBC; EFN B2; EFNB 2; EFNB2; Eph related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 5; Ephrin-B2; EphrinB2; EPLG 5; EPLG5; Htk L; HTK ligand; HTK-L; HTKL; LERK 5; LERK-5; LERK5; Ligand of eph related kinase 5 antibody; MGC126226; MGC126227; MGC126228; OTTMUSP00000024973; Htk-L; ELF-2; NLERK-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293E
  • HEK293F
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • hFc
  • His
  • Fc
  • Fc Chimera
  • FC
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EFNB2-2240H Active Recombinant Human EFNB2, Fc-His tagged HEK293 Fc Met 1-Ala 229
Human EFNB2-1374H Acitve Recombinant Human EFNB2 protein(Met1-Ala229), His&hFc-tagged HEK293 C-His&hFc Met1-Ala229
Human EFNB2-2032H Active Recombinant Human EFNB2 Protein, His-tagged HEK293 His Met 1-Ala 229
Human EFNB2-480H Recombinant Human EFNB2 Mammalian Cell His
Human EFNB2-272H Recombinant Human EFNB2, ENLYFQ tagged Human Cell His
Human EFNB2-3104H Recombinant Human EFNB2 Protein, GST-tagged Wheat Germ GST
Human EFNB2-3191H Recombinant Human EFNB2, His tagged Human Cell His
Human EFNB2-1134H Recombinant Human EFNB2 protein, His & GST-tagged E.coli His/GST Phe42~Val333 (Accession # P52799)
Human EFNB2-5264H Recombinant Human Ephrin-B2, His-tagged HEK293E His
Human EFNB2-6870H Recombinant Human Ephrin-B2, His-tagged E.coli His 28-229aa
Human EFNB2-358H Recombinant Human EFNB2 Protein HEK293 N/A Ile28-Ala229
Human EFNB2-936HCL Recombinant Human EFNB2 cell lysate Human Cell N/A
Human EFNB2-001H Recombinant Human EFNB2 Protein, Fc-His-tagged HEK293E FC/His 1-227
Human EFNB2-2625H Active Recombinant Human EFNB2 protein, His-tagged HEK293 His Ile28-Ala229
Human EFNB2-2035H Recombinant Human EFNB2 Protein (Ile28-Ala229), His tagged E.coli His Ile28-Ala229
Human EFNB2-4235HF Recombinant Full Length Human EFNB2 Protein, GST-tagged In Vitro Cell Free System GST 333 amino acids
Human EFNB2-2836H Recombinant Human EFNB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EFNB2-2836H-B Recombinant Human EFNB2 Protein Pre-coupled Magnetic Beads HEK293
Human EFNB2-3234H Recombinant Human EFNB2 Protein (Ile28-Ala229), C-His tagged Mammalian cells C-His Ile28-Ala229
Human EFNB2-1403H Active Recombinant Human EFNB2 protein, Fc-tagged HEK293 Fc Ser25-Ala168
Human EFNB2-1378H Recombinant Human EFNB2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse EFNB2-882M Active Recombinant Mouse EFNB2 Protein, Fc-tagged HEK293 Fc
Mouse Efnb2-198M Active Recombinant Mouse Efnb2, Fc Chimera Mammalian cells Fc Chimera
Mouse Efnb2-199M Active Recombinant Mouse Efnb2, Fc Chimera, Biotinylated Mammalian cells Fc Chimera
Mouse Efnb2-1734M Recombinant Mouse Ephrin B2, Fc-His Mammalian cells Fc/His
Mouse Efnb2-3315M Active Recombinant Mouse Efnb2 protein, His-tagged HEK293 His Met1-Ala232
Mouse Efnb2-367M Recombinant Mouse Efnb2 Protein, His-tagged Insect Cell His
Mouse EFNB2-2405MCL Recombinant Mouse EFNB2 cell lysate Human Cell N/A
Mouse Efnb2-1377M Recombinant Mouse Efnb2 Protein, Fc/His-tagged HEK293 Fc/His
Mouse Efnb2-131M-B Recombinant Mouse Efnb2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Efnb2-131M Recombinant Mouse Efnb2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Efnb2-5647M Recombinant Mouse Efnb2 Protein (Arg29-Glu227), C-His tagged Mammalian cells C-His Arg29-Glu227
Mouse Efnb2-2756M Recombinant Mouse Efnb2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Efnb2-896M Recombinant Mouse Efnb2 Protein, His-tagged HEK293F N-His Arg29-Glu227
Mouse Efnb2-7194M Recombinant Mouse Efnb2 Protein, His-tagged Insect Cell His 29-232
Mouse Efnb2-1408M Recombinant Mouse Efnb2 Protein, His&GST-tagged E.coli N-His&GST Phe45-Val336
Mouse Efnb2-1409M Recombinant Mouse Efnb2 Protein, His-tagged E.coli N-His Ile27-Ala230
Rat EFNB2-1078R Active Recombinant Rat EFNB2 Protein, Fc-tagged HEK293 Fc
Rat Efnb2-7435R Active Recombinant Rat Efnb2 protein(Met1-Ala229), His-tagged HEK293 C-His Met1-Ala229
Rat EFNB2-1540RCL Recombinant Rat EFNB2 cell lysate Human Cell N/A
Canine EFNB2-3376C Active Recombinant Canine EFNB2 protein(Met1-Ala229), His-tagged HEK293 C-His Met1-Ala229
Canine EFNB2-175C Recombinant Canine EFNB2, Fc tagged Human Cell His
Canine EFNB2-297C Active Recombinant Canine EFNB2 protein(Met1-Ala229), hFc-tagged HEK293 C-hFc Met1-Ala229
Canine EFNB2-965CCL Recombinant Canine EFNB2 cell lysate Human Cell N/A
Homo sapiens (Human) RFL25238HF Recombinant Full Length Human Ephrin-B2(Efnb2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (28-333)
Mus musculus (Mouse) RFL4749MF Recombinant Full Length Mouse Ephrin-B2(Efnb2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-336)
Chicken EFNB2-6387C Recombinant Chicken EFNB2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Efnb2 Related Research Area

Efnb2 involved in several pathways and played different roles in them. We selected most pathways Efnb2 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Efnb2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceARPC3;RNF8;CLTC;JAK1;SEMA7A;CNTN6;PEBP1;ANK2B;ROCK2
Developmental BiologyTCF4;PAQR3A;FOXD3;SPTBN2;LGI4;TRPC7;DRAP1;NR6A1;MEF2B
EPH-Ephrin signalingEFNB3B;EFNA2A;EPHB4B;EFNB3;SDCBP;AP2A2;MYL12B;MYL12A;EPHA2A
EPH-ephrin mediated repulsion of cellsEFNA5;EPHB4B;EFNA2;EPHA4A;EFNB1;AP2B1;EPHA2;EFNA3;AP2S1
EPHB forward signalingEFNB3;ITSN1;GRB7;EFNA5;EFNB2;EFNB1
EPHB-mediated forward signalingITSN1;ARPC1B;EFNB2;ACTR2;CFL1;EFNB1;ACTR3;EFNB2A;EFNB3B
Ephrin B reverse signalingEFNB1;EFNB2;PTPN13
Ephrin signalingEFNB2A;EFNB3B;EPHB3A;EFNB3;MYL12A;EFNB2;EFNB1;EPHB4A;SDCBP

Efnb2 has several biochemical functions, for example, ephrin receptor binding, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Efnb2 itself. We selected most functions Efnb2 had, and list some proteins which have the same functions with Efnb2. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEFNA5B;EFNB3;CDK5R1;CHN1;SRC;EFNA1A;EFNA2;FYN;EPHA7
protein bindingIGFLR1;MASP1;TMPRSS7;IGFBP5;WAS;C17orf59;OFCC1;GADD45A;RAB21
virus receptor activityEFNB3;SLAMF1;TYRO3;ITGA2;NCAM1;ITGB5;PVR;ITGAV;CCR5

Efnb2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Efnb2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Efnb2.

NCK2

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What effect does EphB6 overexpression have on EFNB2? 05/06/2022

EphB6 overexpression up-regulates the expression of its ligand EFNB2.

What diseases is EFNB2 involved in? 01/02/2022

EFNB2 is associated with breast, colon, bladder, cervical and other cancers.

What is the biological function of EFNB2? 05/05/2021

EFNB2 is involved in tissue plasticity, tumorigenesis, and other biological processes.

Where is EFNB2 mainly expressed? 04/10/2021

EFNB2 is widely expressed in tumor vasculature.

What is the association between EFNB2 and BUC cells? 03/12/2021

EFNB2 promotes BUC cell proliferation by inhibiting apoptosis in BUC cells.

How is EphB6 related to EFNB2? 07/09/2019

EFNB2 is one of the physiological ligands of EphB6 that functions by binding to EphB6.

Customer Reviews (3)

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Reviews
01/05/2022

    During the experiment, the technician helped me solve the problems in a timely and accurate manner.

    01/02/2022

      The EFNB2 proteins purchased from your company is suitable for WB.

      01/23/2021

        Received high quality protein products and obtained satisfactory experimental results.

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