EIF6 Protein, eukaryotic translation initiation factor 6

EIF6

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EIF6

Official Full Name eukaryotic translation initiation factor 6
Background Eukaryotic initiation factor 6 (eIF6) is reqiured for the 60S ribosomal subunit assembly in the nucleolus. In the cytoplasm, this protein is bound to 60S ribosome subunits and prevents them from joining 40S ribosome subunits to form 80S ribosomes. eIF6 is
Synonyms EIF6; eukaryotic translation initiation factor 6; EIF3A, integrin beta 4 binding protein , ITGB4BP; b(2)gcn; p27BBP; B4 integrin interactor; p27 beta-4 integrin-binding protein; eukaryotic translation initiation factor 3A; CAB; EIF3A; eIF-6; ITGB4BP; p27
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF6-12391H Recombinant Human EIF6, GST-tagged E.coli GST
    Human EIF6-141H Recombinant Human EIF6 protein, T7-tagged E.coli T7
    Human EIF6-245HCL Recombinant Human EIF6 lysate HEK293 N/A
    Human EIF6-26861TH Recombinant Human EIF6 Wheat Germ N/A
    Human EIF6-2911H Recombinant Human Eukaryotic Translation Initiation Factor 6, T7-tagged E.coli T7
    Human EIF6-3218H Recombinant Human EIF6 Protein, GST-tagged Wheat Germ GST
    Mouse EIF6-5119M Recombinant Mouse EIF6 Protein Mammalian Cell His
    Rat EIF6-2072R Recombinant Rat EIF6 Protein Mammalian Cell His
    Chicken EIF6-2544C Recombinant Chicken EIF6 Mammalian Cell His
    Zebrafish EIF6-11182Z Recombinant Zebrafish EIF6 Mammalian Cell His

    EIF6 involved in several pathways and played different roles in them. We selected most pathways EIF6 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome biogenesis in eukaryotes SBDS; NAT10; NVL; RBM28; ACK2; SPATA5; REX1; SMFN; RPP40; UTP14C

    EIF6 has several biochemical functions, for example, protein binding, ribosomal large subunit binding, ribosome binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF6 itself. We selected most functions EIF6 had, and list some proteins which have the same functions with EIF6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CTLA4; KCNB1; ARHGEF1; PVRL2; CXXC1; ANO2; MAB21L3; CD5; PLEKHG4; STRN
    ribosomal large subunit binding CPEB2; EIF6; MRRF; NPM1; RBM3; MALSU1; OLA1; NMD3
    ribosome binding EIF2S1; EFTUD1; OLA1; CPEB1; NARG1; RPSA; CPEB4; MTRF1L; PPP1R2P9; CPEB1B
    translation initiation factor activity EIF3BA; EIF4H; EIF2S1; EIF4EA; EIF5B; EIF3EB; EIF1AX; EIF5; EIF4E; EIF4A1B

    EIF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF6.

    NREP; EIF2AK2; DHX58; OAS3; Prkcb; q96nr0_human

    Vreugde, S; Ferrai, C; et al. Nuclear myosin VI enhances RNA polymerase II-dependent transcription. MOLECULAR CELL 23:749-755(2006).
    Si, K; Chaudhuri, J; et al. Molecular cloning and functional expression of a human cDNA encoding translation initiation factor 6. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94:14285-14290(1997).

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