Recombinant Human EIF6 protein, T7-tagged
Cat.No. : | EIF6-141H |
Product Overview : | Recombinant human EIF6 (245 aa, Isoform-A) fused with T7 Tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Tag : | T7 |
Form : | 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT. |
AA Sequence : | MASMTGGQQMGRGEFMAVRASFENN CEIGCFAKLTNTYCLVAIGGSENFY SVFEGELSDTIPVVHASIAGCRIIG RMCVGNRHGLLVPNNTTDQELQHIR NSLPDTVQIRRVEERLSALGNVTTC NDYVALVHPDLDRETEEILADVLKV EVFRQTVADQVLVGSYCVFSNQGGL VHPKTSIEDQDELSSLLQVPLVAGT VNRGSEVIAAGMVVNDWCAFCGLDT TSTELSVVESVFKLNEAQPSTIATS MRDSLIDSLT |
Purity : | >90% by SDS-PAGE |
Applications : | 1. May be used for in vitro EIF6 mediated ribosome biogenesis pathway regulation study with intracellular delivery of this protein.2. As soluble / native protein, may be used as enzymatic substrate protein for kinase and ubiquitin assay development.3. May be used for mapping EIF6 protein-protein interaction.4. Potential diagnostic biomarker for various diseases, such as Shwachman-Diamond syndrome.5. May be used as antigen for specific antibody development. |
Storage : | Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days. |
Gene Name : | EIF6 eukaryotic translation initiation factor 6 [ Homo sapiens ] |
Official Symbol : | EIF6 |
Synonyms : | EIF6; eukaryotic translation initiation factor 6; EIF3A, integrin beta 4 binding protein , ITGB4BP; b(2)gcn; p27BBP; B4 integrin interactor; p27 beta-4 integrin-binding protein; eukaryotic translation initiation factor 3A; CAB; EIF3A; eIF-6; ITGB4BP; p27(BBP); |
Gene ID : | 3692 |
mRNA Refseq : | NM_002212 |
Protein Refseq : | NP_002203 |
MIM : | 602912 |
UniProt ID : | P56537 |
Chromosome Location : | 20q11.2 |
Pathway : | Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem; Translation Factors, organism-specific biosystem; |
Function : | protein binding; ribosome binding; translation initiation factor activity; |
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EIF6-1729R | Recombinant Rat EIF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF6-2728M | Recombinant Mouse EIF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF6-12391H | Recombinant Human EIF6 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
EIF6-245HCL | Recombinant Human EIF6 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionEIF6 helps cells respond to stress, adapting protein synthesis under nutrient deprivation or hypoxic conditions.
EIF6 is crucial for ribosome assembly and regulates the initiation of protein synthesis in eukaryotic cells.
EIF6 plays a role in selectively controlling the translation of specific mRNA molecules.
EIF6 contributes to cellular growth by facilitating efficient protein synthesis, necessary for cell proliferation.
Changes in EIF6 activity can impact metabolic processes, potentially leading to the development of metabolic disorders.
Dysregulation of EIF6 can lead to abnormal protein synthesis, contributing to cancer development and progression.
EIF6 influences cell cycle and differentiation by modulating the synthesis of key regulatory proteins.
Customer Reviews (3)
Write a reviewDependable expertise in protein engineering, unmatched in quality.
Invaluable protein-protein interaction assays, integral to our research.
Swift protein sequencing, invaluable for protein identification.
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