|Official Full Name||ELAV like RNA binding protein 1|
|Background||The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3 untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]|
|Synonyms||ELAVL1; ELAV like RNA binding protein 1; HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ELAVL1 involved in several pathways and played different roles in them. We selected most pathways ELAVL1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELAVL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|AMPK signaling||ELAVL1; CDKN1A; PPARGC1B; CPT1A; EIF4EBP1; ADRa1A; CPT1C; INS-IGF2; SLC2A4RG; CPT1B|
|AMPK signaling pathway||RAB11B; RPS6KB1; RPS6KB2; RHEB; FBP2; PPP2CB; FBP1; CCND1; PRKAA1; IRS2|
|Gene Expression||ADAT2; ZNF124; LRPPRC; ZNF3; MTERF; GPR19; ZNF566; SFRS3A; TUBB3; ZNF189|
|HuR (ELAVL1) binds and stabilizes mRNA||SET; ANP32A; HUG; ELAVL1; SETA; SETB|
|Regulation of mRNA stability by proteins that bind AU-rich elements||TNPO1; ELAVL1; SETB; SETA; SET; ZFP36L1A; HUG; ANP32A; HNRNPD; ZFP36L1|
ELAVL1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ELAVL1 itself. We selected most functions ELAVL1 had, and list some proteins which have the same functions with ELAVL1. You can find most of the proteins on our site.
|AU-rich element binding||ZFP36L1; HNRNPA0; ELAVL1; EXOSC7; EXOSC8; ZFP36; NUDT21; TIAL1; ELAVL4; EXOSC4|
|RNA binding||DNMT1; RPL14; CPSF1; RNMTL1B; KHDC1C; RBMS2; EIF4E3; RTCD1; EIF2S2; IGHMBP2|
|double-stranded RNA binding||DDX21; DHX15; AGO2; STRBP; ACTN1; DHX30; MBNL1; HMGB1; TLR7; BARHL1|
|mRNA 3-UTR AU-rich region binding||CPEB2; ELAVL1; CPEB3; CPSF1; ZFP36; CPEB1B; CPEB1|
|mRNA 3-UTR binding||RBMS3; CARHSP1; KHSRP; LARP1; RBM24A; TES; ANGEL2; FXR1; RNF20; CPEB3|
|mRNA binding||C1QBP; SOSTDC1B; RPS5; HNRNPAB; MRPS7; UHMK1; NCBP2; G3BP1; RBMY1A1; FMR1|
|nucleotide binding||NUBP1; RBM12B1; RBM22; HNRNPA1A; P2RX4A; PTBP2A; POLA1; RBM12; GNAO1B; NXF2|
|poly(A) RNA binding||MCAT; FAM98C; DMGDH; UTP18; LSM6; GSPT2; SECISBP2; SRRT; SYF2; GFM1|
|protein binding||EIF4E; SPG7; LAX1; ERLIN1; RNF43; ADSS; PSMD3; DNASE1; APOBEC3G; LENG1|
|protein kinase binding||CCNT2A; MAG; CAMK2N2; RPS6; HCLS1; CCNE1; MSN; PPP1R12A; CDK5RAP2; FBXW5|
ELAVL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELAVL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELAVL1.
SDCBP; q99ib8-pro_0000045602; TOP1; Smurf2; UBC; SF3A2; RBFOX2; GJB3; PTBP1; NOS3