Recombinant Human ELAVL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ELAVL1-6668H
• Product Overview: ELAVL1 MS Standard C13 and N15-labeled recombinant protein (NP_001410) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 36.1 kDa
• AA Sequence: MSNGYEDHMAEDCRGDIGRTNLIVN YLPQNMTQDELRSLFSSIGEVESAK LIRDKVAGHSLGYGFVNYVTAKDAE RAINTLNGLRLQSKTIKVSYARPSS EVIKDANLYISGLPRTMTQKDVEDM FSRFGRIINSRVLVDQTTGLSRGVA FIRFDKRSEAEEAITSFNGHKPPGS SEPITVKFAANPNQNKNVALLSQLY HSPARRFGGPVHHQAQRFRFSPMGV DHMSGLSGVNVPGNASSGWCIFIYN LGQDADEGILWQMFGPFGAVTNVKV IRDFNTNKCKGFGFVTMTNYEEAAM AIASLNGYRLGDKILQVSFKTNKSH KTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ELAVL1 ELAV like RNA binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: ELAVL1
• Synonyms: ELAVL1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); HUR; ELAV-like protein 1; embryonic lethal; abnormal vision; drosophila; homolog like 1; Hu antigen R; Hua; HuR; MelG; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV1
• Gene ID: 1994
• mRNA Refseq: NM_001419
• Protein Refseq: NP_001410
• MIM: 603466
• UniProt ID: Q15717