|Official Full Name||enolase 1, (alpha)|
|Background||This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.|
|Synonyms||ENO1; enolase 1, (alpha); ENO1L1, MPB1; alpha-enolase; c-myc promoter-binding protein-1; MBP 1; PPH; enolase-alpha; tau-crystallin; non-neural enolase; alpha enolase like 1; phosphopyruvate hydratase; plasminogen-binding protein; MYC promot|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ENO1 involved in several pathways and played different roles in them. We selected most pathways ENO1 participated on our site, such as Glycolysis / Gluconeogenesis, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glycolysis / Gluconeogenesis||ADH2-2; PGAM2; FBP1B; PFKM; LDHBA; ALDH3A2A; ALDH2.2; MINPP1A; PKM2; HKDC1|
|Metabolic pathways||CEPT1B; POLA1; PDXK; MAN1A1; POC1BL; GALNS; PLA2G2E; PAFAH1B3; UMPS; QRSL1|
|Carbon metabolism||PKM2; PKM; SDHDA; GOT2B; MCEE; IDH3G; ackA; pykF; DLDH; ENO1|
|Biosynthesis of amino acids||PAH; PSAT1; PYCR1B; PFKMA; TKT; PKM; PGAM2; GPT2L; MAT1A; PGAM1B|
|RNA degradation||CNOT2; PABPC5; EXOSC6; LSM5; PNPT1; EXOSC5; LSM7; PFKM; ENO1; EXOSC1|
|HIF- signaling pathway||RELA; TLR4; IL6; PDK1; PIK3CA; BCL2; ENO2; CAMK2D; PDHA2; PIK3R2|
ENO1 has several biochemical functions, for example, DNA binding, GTPase binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ENO1 itself. We selected most functions ENO1 had, and list some proteins which have the same functions with ENO1. You can find most of the proteins on our site.
|DNA binding||PRRX1B; SMUG1; ZFP93; RFXAP; CEBPA; HIST1H2BI; CREB1B; CALR; PRDM10; SPZ1|
|GTPase binding||GNB2; RAB3D; GNB3; GOLGA4; SPTBN1; RASA1; HSP90AA1; EPRS; STOML2; ENO1|
|magnesium ion binding||IRAK4; ATP8A1; WRN; ZNF143B; ENO1B; RPS6KA6; PRTFDC1; CDC42BPA; SRR; GTPBP5|
|phosphopyruvate hydratase activity||ENO1; ENO1B; ENO4; ENO2; ENO3; ENO1A; GM5506|
|poly(A) RNA binding||NOC3L; RPLP0; HIST1H4J; PEG10; SSRP1; RPL23; EXOSC6; DDX56; MAGOH; CLNS1A|
|protein binding||IRF1; AHSP; SGCG; FPR1; RALB; CD70; C22orf29; KCND2; CDK4; cgr2b|
|transcription corepressor activity||MSC; TFCP2L1; GMNN; SKIL; CDYL; PROX1; PRMT5; LDB1; PBXIP1; DAXX|
|transcription factor activity, sequence-specific DNA binding||CREB3L3L; RARA; TCF7L1B; ALS2CR8; RORCB; ZNF302; CREM; ZNF287; ZFP28; SOX13|
ENO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENO1.
YWHAZ; PCNA; VCAM1; ACHE; Akt2; 2-phospho-d-glyceric acid; PDE4DIP; MAP3K7; RIPK2; ACTB