eno1
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  • Official Full Name
  • enolase 1, (alpha)
  • Background
  • This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
  • Synonyms
  • ENO1; enolase 1, (alpha); ENO1L1, MPB1; alpha-enolase; c-myc promoter-binding protein-1; MBP 1; PPH; enolase-alpha; tau-crystallin; non-neural enolase; alpha enolase like 1; phosphopyruvate hydratase; plasminogen-binding protein; MYC promot
Cat.#:ENO1-3309HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ENO1 Protein, GST-tagged
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Cat.#:Eno1-244MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Eno1 Protein, His-tagged, Bioactivity Validated
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Cat.#:ENO1-12451HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ENO1, His-tagged
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Cat.#:ENO1-1814HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Enolase 1, (Alpha)
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Cat.#:ENO1-2512HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ENO1, His tagged
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Cat.#:ENO1-2513HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ENO1 protein, His-tagged
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Cat.#:ENO1-28561THTag:
Source (Host):Species:Human
Product nameRecombinant Human ENO1
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Cat.#:ENO1-28565THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ENO1
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Cat.#:Eno1-103MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Eno1 protein, His-tagged
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Cat.#:ENO1-5203MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ENO1 Protein
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Cat.#:Eno1-207RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Eno1 protein, His-tagged
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Cat.#:ENO1-2098RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ENO1 Protein
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Cat.#:ENO1-493CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ENO1 Protein, His-tagged
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Cat.#:ENO1-1474RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ENO1 Protein, His-tagged
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Cat.#:ENO1-6677CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ENO1
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Cat.#:ENO1-6975CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle ENO1 protein, His-tagged
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Cat.#:ENO1-6599HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ENO1 293 Cell Lysate
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Cat.#:Kit-0324Tag:
Source (Host):Species:
Product nameENO1 Human Activity Assay Kit
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Involved Pathway

ENO1 involved in several pathways and played different roles in them. We selected most pathways ENO1 participated on our site, such as Glycolysis / Gluconeogenesis, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycolysis / Gluconeogenesis
TPI1A; ADH2-1; HK1; ALDH9A1; ENO1; ALDH9A1A.1; GAPDH; ALDH3A1; PDHA1B; ALDOCA
Metabolic pathways
MAN2A1; UGT1A6B; PAFAH1B1; SC4MOL; GUK1; MAN1B1; Atp5k; DAD1; CYP4A12A; GALCB
Carbon metabolism
PGAM1; FH; PDHA2; PRPS2; ALDOAB; AGXTB; ALDOB; PGAM2; HK2; GPT2L
Biosynthesis of amino acids
ALDOB; PAH; ALDH18A1; ALDOC; IDH3B; PKLR; PFKMA; PGAM2; AADAT; RPE
RNA degradation
LSM2; CNOT6; EDC3; CNOT6L; LSM3; EXOSC8; EXOSC10; XRN2; ENO1; TOB2
HIF- signaling pathway
PIK3CD; INS; PIK3R2; Trf; PIK3CG; PDHB; ENO2; IGF1; IFNGR2; STAT3

Protein Function

ENO1 has several biochemical functions, for example, DNA binding, GTPase binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ENO1 itself. We selected most functions ENO1 had, and list some proteins which have the same functions with ENO1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein HIST1H111R; HIST1H3G; BRPF1; NFE2L1B; ZNF266; NKX6.2; AIFM1; DBX1A; DNMT3A; IRX6A
Function GTPase binding
Related Protein GNB2; HSP90AA1; VPS41; BNIP3; MARCH5; STOML2; GNB3; GM5506; GOLGA4; YBX1
Function magnesium ion binding
Related Protein ERN1; NUDT7; ABL2; IDH3B; NLRC4; NIM1K; TOP2A; Atp8a2; ILVBL; PPM1A
Function phosphopyruvate hydratase activity
Related Protein ENO4; GM5506; ENO1A; ENO1; ENO1B; ENO2; ENO3
Function poly(A) RNA binding
Related Protein RPS4X; ETF1; FASTKD2; GDI2; HLA-A; TRMT1; PURA; SCG3; RPGR; ZC3H18
Function protein binding
Related Protein TRAF4; TULP1; COX5A; DCUN1D4; SETD2; DLX2; RGS6; MAP3K2; NECAB3; MFF
Function transcription corepressor activity
Related Protein POU1F1; MYBBP1A; SAP30; TRIM28; ZMYND11; YWHAB; MAP3K10; SAP18; NRIP1; ZNF136
Function transcription factor activity, sequence-specific DNA binding
Related Protein FOXM1; PBX3B; ZIC1; ZNF23; MYCB; TAF5L; NFE2L2; BHLHE40; DMRTC2; TAF1B

Interacting Protein

ENO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENO1.
YWHAZ; PCNA; VCAM1; ACHE; Akt2; 2-phospho-d-glyceric acid; PDE4DIP; MAP3K7; RIPK2; ACTB

ENO1 Related Articles

Petit, FM; Serres, C; et al. Moonlighting proteins in sperm-egg interactions. BIOCHEMICAL SOCIETY TRANSACTIONS 42:1740-1743(2014).
Amedei, A; Niccolai, E; et al. Pancreatic cancer: Role of the immune system in cancer progression and vaccine-based immunotherapy. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3354-3368(2014).