ENO1

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ENO1

Official Full Name enolase 1, (alpha)
Background This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
Synonyms ENO1; enolase 1, (alpha); ENO1L1, MPB1; alpha-enolase; c-myc promoter-binding protein-1; MBP 1; PPH; enolase-alpha; tau-crystallin; non-neural enolase; alpha enolase like 1; phosphopyruvate hydratase; plasminogen-binding protein; MYC promot
    • Species :
    • Cattle
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ENO1-002H Recombinant Human ENO1 Protein E.coli
    Human ENO1-004H Recombinant Human ENO1 Protein E.coli
    Human ENO1-2760H Recombinant Human ENO1 Protein (2-434 aa), His-Myc-tagged Insect Cell His/Myc
    Mouse Eno1-2827M Recombinant Mouse Eno1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human ENO1-3995H Recombinant Human ENO1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ENO1-12451H Recombinant Human ENO1, His-tagged E.coli His
    Human ENO1-1814H Recombinant Human Enolase 1, (Alpha) E.coli N/A
    Human ENO1-2512H Recombinant Human ENO1, His tagged E.coli His
    Human ENO1-2513H Recombinant Human ENO1 protein, His-tagged HEK293 His
    Human ENO1-28561TH Recombinant Human ENO1 N/A
    Human ENO1-28565TH Recombinant Human ENO1 E.coli N/A
    Human ENO1-3309H Recombinant Human ENO1 Protein, GST-tagged Wheat Germ GST
    Human ENO1-6599HCL Recombinant Human ENO1 293 Cell Lysate HEK293 N/A
    Mouse Eno1-103M Recombinant Mouse Eno1 protein, His-tagged E.coli His
    Mouse Eno1-244M Recombinant Mouse Eno1 Protein, His-tagged, Bioactivity Validated E.coli His
    Mouse ENO1-5203M Recombinant Mouse ENO1 Protein Mammalian Cell His
    Rat Eno1-207R Recombinant Rat Eno1 protein, His-tagged E.coli His
    Rat ENO1-2098R Recombinant Rat ENO1 Protein Mammalian Cell His
    Cynomolgus Monkey ENO1-493C Recombinant Cynomolgus ENO1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ENO1-1474R Recombinant Rhesus monkey ENO1 Protein, His-tagged Mammalian Cell His
    Chicken ENO1-6677C Recombinant Chicken ENO1 Mammalian Cell His
    Cattle ENO1-6975C Recombinant Cattle ENO1 protein, His-tagged E.coli His
    Kit-0324 ENO1 Human Activity Assay Kit N/A

    ENO1 involved in several pathways and played different roles in them. We selected most pathways ENO1 participated on our site, such as Glycolysis / Gluconeogenesis, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis ADH2-2; PGAM2; FBP1B; PFKM; LDHBA; ALDH3A2A; ALDH2.2; MINPP1A; PKM2; HKDC1
    Metabolic pathways CEPT1B; POLA1; PDXK; MAN1A1; POC1BL; GALNS; PLA2G2E; PAFAH1B3; UMPS; QRSL1
    Carbon metabolism PKM2; PKM; SDHDA; GOT2B; MCEE; IDH3G; ackA; pykF; DLDH; ENO1
    Biosynthesis of amino acids PAH; PSAT1; PYCR1B; PFKMA; TKT; PKM; PGAM2; GPT2L; MAT1A; PGAM1B
    RNA degradation CNOT2; PABPC5; EXOSC6; LSM5; PNPT1; EXOSC5; LSM7; PFKM; ENO1; EXOSC1
    HIF- signaling pathway RELA; TLR4; IL6; PDK1; PIK3CA; BCL2; ENO2; CAMK2D; PDHA2; PIK3R2

    ENO1 has several biochemical functions, for example, DNA binding, GTPase binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ENO1 itself. We selected most functions ENO1 had, and list some proteins which have the same functions with ENO1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding PRRX1B; SMUG1; ZFP93; RFXAP; CEBPA; HIST1H2BI; CREB1B; CALR; PRDM10; SPZ1
    GTPase binding GNB2; RAB3D; GNB3; GOLGA4; SPTBN1; RASA1; HSP90AA1; EPRS; STOML2; ENO1
    magnesium ion binding IRAK4; ATP8A1; WRN; ZNF143B; ENO1B; RPS6KA6; PRTFDC1; CDC42BPA; SRR; GTPBP5
    phosphopyruvate hydratase activity ENO1; ENO1B; ENO4; ENO2; ENO3; ENO1A; GM5506
    poly(A) RNA binding NOC3L; RPLP0; HIST1H4J; PEG10; SSRP1; RPL23; EXOSC6; DDX56; MAGOH; CLNS1A
    protein binding IRF1; AHSP; SGCG; FPR1; RALB; CD70; C22orf29; KCND2; CDK4; cgr2b
    transcription corepressor activity MSC; TFCP2L1; GMNN; SKIL; CDYL; PROX1; PRMT5; LDB1; PBXIP1; DAXX
    transcription factor activity, sequence-specific DNA binding CREB3L3L; RARA; TCF7L1B; ALS2CR8; RORCB; ZNF302; CREM; ZNF287; ZFP28; SOX13

    ENO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENO1.

    YWHAZ; PCNA; VCAM1; ACHE; Akt2; 2-phospho-d-glyceric acid; PDE4DIP; MAP3K7; RIPK2; ACTB

    Petit, FM; Serres, C; et al. Moonlighting proteins in sperm-egg interactions. BIOCHEMICAL SOCIETY TRANSACTIONS 42:1740-1743(2014).
    Amedei, A; Niccolai, E; et al. Pancreatic cancer: Role of the immune system in cancer progression and vaccine-based immunotherapy. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3354-3368(2014).

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