FBXO31 Protein, F-box protein 31


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Official Full Name F-box protein 31
Background Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
Synonyms FBXO31; F-box protein 31; F box only protein 31; F-box only protein 31; FBX14; Fbx31; FBXO14; MGC15419; DKFZp434B027; DKFZp434J1815; FBX31_HUMAN; FLJ22477; MGC9527; pp2386; Putative breast cancer tumor suppressor; SCF ubiquitin ligase specificity factor; putative breast cancer tumor-suppressor
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FBXO31-28814TH Recombinant Human FBXO31, His-tagged E.coli His
    Human FBXO31-3934H Recombinant Human FBXO31 Protein, GST-tagged Wheat Germ GST
    Human FBXO31-6298HCL Recombinant Human FBXO31 293 Cell Lysate HEK293 N/A
    Mouse FBXO31-5743M Recombinant Mouse FBXO31 Protein Mammalian Cell His
    Rat FBXO31-2294R Recombinant Rat FBXO31 Protein Mammalian Cell His
    Rhesus Macaque FBXO31-1662R Recombinant Rhesus monkey FBXO31 Protein, His-tagged Mammalian Cell His

    FBXO31 involved in several pathways and played different roles in them. We selected most pathways FBXO31 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    FBXO31 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO31 itself. We selected most functions FBXO31 had, and list some proteins which have the same functions with FBXO31. You can find most of the proteins on our site.

    Function Related Protein

    FBXO31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO31 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO31.

    SKP1; FAM58A; PDLIM1; MYH6; PRPS1; STX3; CUL1; EFR3A; QSER1; C18orf21; EDRF1; ZCCHC9; Kctd5; MRPS27; DNAJC19; CEP170P1; Skp1

    Zhang, XC; Kong, Y; et al. F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a. ONCOTARGET 5:6178-6190(2014).
    Seeley, AH; Durham, MA; et al. Macrocerebellum, Epilepsy, Intellectual Disability, and Gut Malrotation in a Child With a 16q24.1-q24.2 Contiguous Gene Deletion. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2062-2068(2014).

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