Recombinant Mouse Fbxo31 Protein, Myc/DDK-tagged

• Cat.No.: Fbxo31-2967M
• Product Overview: Purified recombinant protein of mouse full-length F-box protein 31 (Fbxo31), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fbxo31 F-box protein 31 [ Mus musculus (house mouse) ]
• Official Symbol: Fbxo31
• Synonyms: FBXO31; F-box protein 31; F-box only protein 31; F-box only protein 14; Fbx14; Fbxo14; 1110003O08Rik; 2310046N15Rik
• Gene ID: 76454
• mRNA Refseq: NM_133765
• Protein Refseq: NP_598526
• UniProt ID: www.uniprot.org/uniprot/Q3TQF0