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FCRL2

  • Official Full Name

    Fc receptor-like 2

  • Overview

    This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
  • Synonyms

    FCRL2; Fc receptor-like 2; SH2 domain containing phosphatase anchor protein 1 , SPAP1; Fc receptor-like protein 2; CD307b; FCRH2; IRTA4; fcR-like protein 2; IFGP family protein 4; fc receptor homolog 2; immunoglobulin superfamily Fc receptor, gp42; SH2 do;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus monkey
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • GST
  • hIgG1
  • hIgG4
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FCRL2-497H Active Recombinant Human Fc Receptor-Like 2, His-tagged Mammalian cells His
Human FCRL2-750H Recombinant Human FCRL2 Protein, His-tagged HEK293 His
Human FCRL2-4008H Recombinant Human FCRL2 Protein, GST-tagged Wheat Germ GST
Human FCRL2-6275HCL Recombinant Human FCRL2 293 Cell Lysate HEK293 N/A
Human FCRL2-5654H Recombinant Human FCRL2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FCRL2-2938H Recombinant Human FCRL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FCRL2-2938H-B Recombinant Human FCRL2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Fcrl2-5495M Recombinant Mouse Fcrl2 Protein (Asn18-Phe509), C-Fc tagged Mammalian cells C-Fc Asn18-Phe509
Rhesus monkey FCRL2-1713R Recombinant Rhesus Monkey FCRL2 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey FCRL2-1712R Recombinant Rhesus Monkey FCRL2 Protein HEK293 N/A
Rhesus monkey FCRL2-1714R Recombinant Rhesus Monkey FCRL2 Protein, hIgG4-tagged HEK293 hIgG4
Chicken FCRL2-3690C Recombinant Chicken FCRL2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FCRL2 Related Articles
  • FCRL2 Related Research Area

FCRL2 involved in several pathways and played different roles in them. We selected most pathways FCRL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FCRL2 has several biochemical functions, for example, SH3/SH2 adaptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL2 itself. We selected most functions FCRL2 had, and list some proteins which have the same functions with FCRL2. You can find most of the proteins on our site.

Function Related Protein
SH3/SH2 adaptor activityLAT;SH2D2A;SH2B2;LASP1;NCK2;GAB1;PTPN11;TOB1;SLA2
protein bindingFAM122A;EGF;KCTD1;Chrng;RAD51C;PAEP;SPRTN;EIF4EBP3;LRIF1

FCRL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL2.

NCK2

Shabani, M; Bayat, AA; et al. Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling. IMMUNOLOGY 143:341-353(2014).
Disanto, G; Sandve, GK; et al. DNase hypersensitive sites and association with multiple sclerosis. HUMAN MOLECULAR GENETICS 23:942-948(2014).
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