• Official Full Name
  • Fc receptor-like 2
  • Background
  • This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
  • Synonyms
  • FCRL2; Fc receptor-like 2; SH2 domain containing phosphatase anchor protein 1 , SPAP1; Fc receptor-like protein 2; CD307b; FCRH2; IRTA4; fcR-like protein 2; IFGP family protein 4; fc receptor homolog 2; immunoglobulin superfamily Fc receptor, gp42; SH2 do
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCRL2 Protein, GST-tagged
Source (Host):NS0Species:Human
Product nameRecombinant Human Fc Receptor-Like 2, His-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCRL2 Protein, His-tagged
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL2 Protein
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL2 Protein, hIgG1-tagged
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL2 Protein, hIgG4-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FCRL2
Source (Host):Species:Human
Product nameRecombinant Human FCRL2 293 Cell Lysate
Source (Host):Species:Human
Product nameAnti-Human FCRL2 MAb Stable Cell Line-CHO
Source (Host):Species:Human
Product nameAnti-Human FCRL2 F(ab) Stable Cell Line-CHO
Source (Host):Species:Human
Product nameAnti-Human FCRL2 scFv Stable Cell Line-CHO

Protein Function

FCRL2 has several biochemical functions, for example, SH3/SH2 adaptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL2 itself. We selected most functions FCRL2 had, and list some proteins which have the same functions with FCRL2. You can find most of the proteins on our site.
Related Protein
Function SH3/SH2 adaptor activity
Related Protein SH3BP2; ITSN2; GRB10; EPS8; LAT; SOCS2; SHB; HSH2D; GRB2; SH2D2A
Function protein binding
Related Protein PLN; EWSR1; KEL; ROPN1; AAK1; NUP37; RBM10; DDAH2; SOX30; MT1H

Interacting Protein

FCRL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL2.

FCRL2 Related Articles

Shabani, M; Bayat, AA; et al. Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling. IMMUNOLOGY 143:341-353(2014).
Disanto, G; Sandve, GK; et al. DNase hypersensitive sites and association with multiple sclerosis. HUMAN MOLECULAR GENETICS 23:942-948(2014).