fcrl5
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  • Official Full Name
  • Fc receptor-like 5
  • Background
  • Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 function as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role for the pathogenesis of B-cell lymphoma.
  • Synonyms
  • FCRL5; Fc receptor-like 5; Fc receptor-like protein 5; BXMAS1; CD307e; FCRH5; IRTA2; fcR-like protein 5; fc receptor homolog 5; immune receptor translocation-associated protein 2; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); CD307; PRO820; FLJ00333; FLJ00397; RP11-217A12.1; MGC119590; MGC119592; MGC119593; DKFZp667F216; DKFZp667E2019
Cat.#:FCRL5-4010HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCRL5 Protein
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Cat.#:FCRL5-4011HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCRL5 Protein, GST-tagged
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Cat.#:FCRL5-506HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Fc Receptor-Like 5, His-tagged
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Cat.#:Fcrl5-503MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Fc receptor-like 5, His-tagged
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Cat.#:FCRL5-12831HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCRL5, His-tagged
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Cat.#:FCRL5-379HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human FCRL5, His-tagged
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Cat.#:FCRL5-5798MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FCRL5 Protein
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Cat.#:Fcrl5-871MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Fcrl5 Protein, His-tagged
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Cat.#:FCRL5-1706RTag:N/A
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL5 Protein
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Cat.#:FCRL5-1707RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL5 Protein, hIgG1-tagged
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Cat.#:FCRL5-1708RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey FCRL5 Protein, hIgG4-tagged
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FCRL5 Related Articles

Franco, A; Damdinsuren, B; et al. Human Fc Receptor-Like 5 Binds Intact IgG via Mechanisms Distinct from Those of Fc Receptors. JOURNAL OF IMMUNOLOGY 190:5739-5746(2013).
Elkins, K; Zheng, B; et al. FcRL5 as a Target of Antibody-Drug Conjugates for the Treatment of Multiple Myeloma. MOLECULAR CANCER THERAPEUTICS 11:2222-2232(2012).