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FGF11

Official Full Name

fibroblast growth factor 11
Overview

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development.
Synonyms

FGF11; fibroblast growth factor 11; FHF3; fibroblast growth factor homologous factor 3; FLJ16061; MGC45269; MGC102953; FGF 11; FGF-11; FGF11_HUMAN; FHF 3; FHF-3; OTTHUMP00000135275;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E. coli
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

C
His
GST
His (Fc)
Avi
His|T7

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FGF11-8154H	Recombinant Human FGF11 protein, His & T7-tagged	E.coli	His/T7	Leu44~His212 (Accession# Q92914)	Inquiry
Human	FGF11-104H	Active Recombinant Human FGF11 Protein (Pro64-Pro225), C-His tagged, Animal-free, Carrier-free	E.coli	C-His	Pro64-Pro225	Inquiry
Human	FGF11-4101H	Recombinant Human FGF11 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FGF11-025H	Recombinant Human FGF11 Protein	E. coli			Inquiry
Human	FGF11-103H	Active Recombinant Human FGF11 Protein (Met1-Pro225), C-His tagged, Animal-free, Carrier-free	E.coli	C-His	Met1-Pro225	Inquiry
Mouse	FGF11-5839M	Recombinant Mouse FGF11 Protein	Mammalian Cell	His		Inquiry
Mouse	FGF11-3226M	Recombinant Mouse FGF11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	FGF11-3226M-B	Recombinant Mouse FGF11 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
FGF11 Related Research Area
FGF11 Related Signal Pathway

FGF11 involved in several pathways and played different roles in them. We selected most pathways FGF11 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	MAPKAPK2;RAF1;GADD45G;HSP70;MAPK3;FGF10A;MAPK10;MAPK14B;AKT1
Ras signaling pathway	CALM4;PLA2G3;ANGPT4;PDGFC;CDC42;PIK3CA;MET;GNG11;RGL2
Rap signaling pathway	PRKCA;KIT;PDGFA;MET;FLT1;CALML3;PDGFB;MAGI1;GNAO1
PIK-Akt signaling pathway	PKN3;IL2RA;ITGA9;COL6A6;GNG7;PKN1;THBS2;THBS4;TSC2
Regulation of actin cytoskeleton	APC2;SOS1;RAC1;MYH10;IQGAP3;ITGB2;PIP4K2B;PIK3CB;FGF13
Pathways in cancer	AKT1;FLT3;EP300;BMP2;MAP2K1;WNT10B;PLD1;ZBTB16;PRKCA
Melanoma	FGF4;PIK3CB;PIK3R2;HRAS;AKT1;PDGFD;PIK3CA;FGF16;PDGFB

FGF11 has several biochemical functions, for example, growth factor activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF11 itself. We selected most functions FGF11 had, and list some proteins which have the same functions with FGF11. You can find most of the proteins on our site.

Function	Related Protein
growth factor activity	BMP6;PDGFC;Pdgfa&Pdgfb;GMFG;NRG3;BMP15;EPGN;FGF3;LACRT
receptor binding	HNF4A;HACL1;NCR3;PVRL3;MSTN;CRTAM;Fert2;HAMP;FGF18A

FGF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF11.

FGF Family

FGF Ligands

Fibroblast Growth Factor (FGF)